| 100% | SALVIA | 6 | Plant known as "seer's sage" because of its hallucinatory effect |
| 42% | PICODEGALLO | 11 | Condiment also known as salsa bandera because it shares the colors of the Mexican flag |
| 38% | END | 3 | "It's the ___ of the world as we know it" |
| 38% | OPORTO | 6 | City north of Lisbon, as it's sometimes known |
| 38% | EPCOT | 5 | Experimental Prototype Community of Tomorrow, as it's better known |
| 35% | END | 3 | R.E.M.'s "It's the ___ of the World as We Know It" |
| 35% | SILENTE | 7 | End of life as we know it? |
| 34% | ABALONE | 7 | The iridescent coating of its shell is known as mother-of-pearl |
| 34% | REM | 3 | "It's the End of the World as We Know It (And I Feel Fine)" band |
| 34% | TRITONE | 7 | Interval known as "the devil in music" on account of its unsettling sound |
| 34% | MISSISSIPPIRIVER | 16 | It was known by the Algonquin as the "Father of Waters" |
| 33% | END | 3 | R.E.M.'s "It's the ___ of the World as We Know It (And I Feel Fine)" |
| 33% | AGAVE | 5 | Plant used in xeriscaping because of its tolerance to drought |
| 32% | GUMWEEDS | 8 | Plants known as "sticky-heads" |
| 32% | IGUANA | 6 | In the Caribbean it's known as "the chicken of the trees" |
| 32% | GRAMMARPOLICE | 13 | People who would object to this clue because of it's punctuation |
| 32% | ETNA | 4 | It's known locally as Mongibello |
| 31% | DELPHI | 6 | Greek city known as home of Apollo's oracle |
| 31% | WELSH | 5 | It's known to locals as Cymraeg |
| 31% | ELLA | 4 | Jenkins known as "The First Lady of Children's Music" |
| 31% | HARTFORDCONNECTICUT | 19 | It's known as "Insurance City" |
| 31% | BURMA | 5 | Myanmar, as it's also known |
| 30% | RUE | 3 | Plant also known as herb-of-grace |
| 30% | NENE | 4 | Bird so named because of its call |
| 30% | KIROV | 5 | Mariinsky Ballet, as it's known internationally |
| 30% | KIROV | 5 | Mariinsky Ballet, as it's also known |
| 30% | PAPAW | 5 | Tropical fruit, as it's sometimes known |
| 30% | ROLLEDR | 7 | Alveolar trill, as it's commonly known |
| 30% | END | 3 | "Its the ___ of the World as We Know It (And I Feel Fine)" (R.E.M. song) |