| 100% | ANNUAL | 6 | Plant that completes its life cycle in one year |
| 38% | PERENNIAL | 9 | Describes a plant that lives more than two years |
| 37% | EVERGREEN | 9 | Plant that doesn't lose its foliage in autumn |
| 36% | PERENNIAL | 9 | A plant that lives or blooms for several years |
| 36% | TWOS | 4 | "Terrible" time in one's life, it is said |
| 36% | FAD | 3 | It's in one year and out the other |
| 36% | AMOEBA | 6 | One that lives in a single cell? |
| 35% | PERENNIAL | 9 | Term for a plant that lives more than two years |
| 35% | TEENAGE | 7 | Period in one's life, between 13 to 19 years |
| 35% | OED | 3 | It took 70 years to complete, in brief |
| 35% | TREY | 4 | Card that has its pips aligned in one row |
| 34% | CARAWAY | 7 | Eurasian plant that bears an aromatic one-seeded fruit used in cooking |
| 33% | TURTLE | 6 | Reptile that lives in its shell and likes water |
| 33% | HONEYBEE | 8 | Flying insect that lives in a hive with its queen |
| 33% | LOTUS | 5 | Plant in Greek mythology whose fruit induced forgetfulness in those who ate it |
| 33% | LOTUS | 5 | Plant in Greek mythology whose fruit-induced forgetfulness in those who ate it |
| 32% | CSI | 3 | One of the 11 4-year senior schools in the City University of New York system that has Danny the Dolphin as its mascot |
| 32% | SELFIE | 6 | Picture type that Oxford Dictionaries named its "Word of the Year" in 2013 |
| 32% | NLEAST | 6 | Div. that, in its first year of existence, produced a World Series champ |
| 31% | ACRE | 4 | State in northwest Brazil ... or one of 37.7 million that it comprises |
| 31% | BEAT | 4 | "___ It," song from 14a that won the Grammy for Record of the Year in 1984 |
| 31% | TITANIC | 7 | Film that was rereleased in 3-D nearly fifteen years after its initial première |
| 31% | DIDNT | 5 | "___ We Almost Have It All," number-one hit by Whitney Houston that received a Grammy nomination for Song of the Year in 1988 |
| 31% | LIFEINYOURYEARS | 15 | "And in the end, it's not the years in your life that count, it's the ___" (Abraham Lincoln) |
| 31% | SLACK | 5 | Go-to app for team chats, files, and workspaces all in one place that makes your work life easier |
| 30% | DET | 3 | Mich. city that's lost over half its population in the past fifty years (abbr.) |
| 30% | BEAUTIFUL | 9 | "What Makes You ___," pop song by One Direction that turned ten years old in 2021 |
| 30% | RAT | 3 | It lives in sewers |
| 30% | SLUR | 4 | In music, a curved line indicating that the notes in its limits be played smoothly, as one phrase |
| 30% | OCEAN | 5 | In June of this year NASA reported that exoplanets with one of these may actually be quite common |