| 100% | LOREN | 5 | Player of Cleopatra in "Two Nights With Cleopatra" |
| 54% | TEXASHOLDEM | 11 | Variant of the card game poker in which each player starts with two cards only |
| 52% | ANTAWN | 6 | __ Jamison, one of two NBA players with 20,000+ points who's not in the Hall of Fame |
| 50% | ASPS | 4 | Two of them bite Cleopatra in "Antony and Cleopatra" |
| 50% | TIAREJENNINGS | 13 | Softball player who won two championships with the University of Oklahoma and who was named Big 12 Freshman of the Year in 2021 (2 wds.) |
| 49% | ERIC | 4 | With 1-Down, player of the Hulk in 2003's "Hulk" |
| 47% | FOURSOME | 8 | Golf competition with two pairs of players |
| 47% | FOURSOMES | 9 | Golf variant with two pairs of players |
| 47% | JEKYLL | 6 | One of two title characters in a book with one title character |
| 46% | CRUE | 4 | One of two words with an umlaut in a metal band's name |
| 45% | ANNA | 4 | Title character of literature in a love triangle with two 66-Across named Alexei |
| 45% | BEER | 4 | Together with lemonade, one of two ingredients in a shandy |
| 45% | AARON | 5 | Hank —, US baseball player who retired in 1976 with a total of 755 home runs |
| 45% | AARON | 5 | Hank ---, US baseball player who retired in 1976 with a total of 755 home runs |
| 44% | DARTS | 5 | Game in which each player starts with a score of 501 |
| 44% | FIBULA | 6 | One of two bones in the lower leg with the tibia |
| 44% | MEME | 4 | Image with two lines of Impact font, in the early days |
| 44% | RICE | 4 | Along with lentils, one of the two main ingredients in idli |
| 44% | BERTLAHR | 8 | Only cast member with two solos in "The Wizard of Oz" |
| 44% | DAVID | 5 | With 34-Across, Red Sox pitcher who won the MLB Comeback Player of the Year Award in 2018 |
| 44% | BACTRIAN | 8 | — camel, creature with two humps used as a beast of burden in deserts of central Asia |
| 44% | OTOOLE | 6 | Player of Priam in "Troy" |
| 44% | OPRAH | 5 | Player of Sethe in "Beloved" |
| 44% | JUDIDENCH | 9 | Player of M in "GoldenEye" |
| 44% | SLOTH | 5 | Along with the anteater, one of two animals in the order Pilosa |
| 43% | ERNIE | 5 | With 35-Across, baseball player who received the Presidential Medal of Freedom in 2013 and died 1/23/15 |
| 43% | PAULMCCARTNEY | 13 | Artist with the most number of Grammy nominations in one night without winning, with 9: 2 wds. |
| 43% | CRIBBAGE | 8 | Game of cards for two to four players using a board with pegs and holes for scoring |
| 43% | UMA | 3 | Player of June in "Henry & June" |
| 43% | ASNER | 5 | Player of Santa in "Elf," 2003 |