| 100% | SPINCITY | 8 | Political sitcom starring Barry Bostwick, 15-Across, 20-Across, and 37-Across that debuted in 1996 (2 wds.) |
| 55% | SUDDENLYSUSAN | 13 | Sitcom starring 15-Across and 32-Across that premiered in 1996 (2 wds.) |
| 46% | THEJEFFERSONS | 13 | Sitcom starring Sherman Hemsley and 15-Across that debuted January 18, 1975 (2 wds.) |
| 45% | THEXFILES | 9 | Paranormal TV series featuring the characters 15-Across, 21-Across, and 41-Across that debuted in 1993 (2 wds.) |
| 44% | FAMILYGUY | 9 | Seth MacFarlane animated series featuring the voices of 15-Across, 26-Across, and 34-Across that debuted in 1999 (2 wds.) |
| 44% | ALLINTHEFAMILY | 14 | Norman Lear sitcom starring 16-Across and 35-Across that debuted in January 1971 (4 wds.) |
| 42% | SUDDENLYSUSAN | 13 | 1996-2000 sitcom starring 15-Across as a magazine writer in San Francisco: 2 wds. |
| 42% | THEGODFATHER | 12 | Oscar-winning film starring 14-Across and 28-Across that debuted in March 1972 (2 wds.) |
| 41% | MEDICALCENTER | 13 | Hospital drama starring James Daly and Chad Everett that debuted in 1969 (2 wds.) |
| 41% | JUSTSHOOTME | 11 | Sitcom starring David Spade that debuted in 1997 and ran for seven seasons (3 wds.) |
| 40% | TOP | 3 | With 57-Across, action film starring 15-Across, 33-Across, and 48-Across that debuted 35 years ago this month (2 wds.) |
| 40% | MARCUSWELBYMD | 13 | Medical drama starring 18-Across and 40-Across that debuted in September 1969 (3 wds.) |
| 39% | THEBRADYBUNCH | 13 | Family sitcom starring Robert Reed and Florence Henderson that debuted in 1969 (3 wds.) |
| 39% | THEWESTWING | 11 | A political drama that debuted in the 90s, starring the likes of Rob Lowe and Martin Sheen: 3 wds. |
| 39% | NASHBRIDGES | 11 | Police procedural set in San Francisco starring 13-Across and 25-Across that began its six-year run in 1996 (2 wds.) |
| 39% | GEORGELOPEZ | 11 | Comedian who starred in a self-titled sitcom from 2002 to 2007, and another that started in 2016: 2 wds. |
| 37% | SONSOFANARCHY | 13 | "Mayans M.C." precursor starring 15-Across as 30-Across that debuted in 2008 (3 wds.) |
| 37% | THEPRACTICE | 11 | Legal drama starring Dylan McDermott that debuted in 1997 and ran for eight seasons (2 wds.) |
| 37% | THEODDCOUPLE | 12 | 1970s Neil Simon sitcom starring 17-Across and 41-Across that debuted 50 years ago (3 wds.) |
| 36% | SAMSMITH | 8 | Grammy-winning singer of "Stay With Me," 15-Across, 20-Across, and 37-Across (2 wds.) |
| 36% | FIRSTDAUGHTER | 13 | Informal political title that could be applied to 15-, 17-, 46-, and 48-Across: 2 wds. |
| 35% | DOCTORODYSSEY | 13 | 2024-2025 medical drama aboard a cruise ship that starred 15-Across and Don Johnson: 2 wds. |
| 35% | DERRYGIRLS | 10 | British sitcom set in Northern Ireland that starred 34-Across as Catholic school student Clare Devlin: 2 wds. |
| 35% | RYANGOSLING | 11 | "Barbie" actor who stars in 15-Across, 35-Across, and 43-Across (2 wds.) |
| 35% | SISTERSISTER | 12 | Former Tia Mowry/Tamera Mowry sitcom that debuted in 1994 (2 wds.) |
| 35% | PAULRUDD | 8 | 15-Across, 22-Across, and 37-Across actor who plays Scott Lang/Ant-Man in the Marvel Cinematic Universe (2 wds.) |
| 34% | LUCYLIU | 7 | 15-Across, 20-Across, and 36-Across actress who voices Master Viper in the "Kung Fu Panda" films (2 wds.) |
| 34% | DOCTORODYSSEY | 13 | Drama that debuted in 2024 that stars Joshua Jackson as a cruise ship physician: 2 wds. |
| 34% | WILLSMITH | 9 | "King Richard" actor who also starred in 15-Across, 26-Across, and 34-Across (2 wds.) |
| 34% | LAFEMMENIKITA | 13 | Action series starring Peta Wilson that debuted in 1997 and ran for five seasons (3 wds.) |