| 100% | RNA | 3 | Polymeric molecule essential in expression of genes: Abbr. |
| 41% | RNA | 3 | Molecule that can interfere in gene expression |
| 38% | TGIF | 4 | Expression of words said in relief by every office-goer when the weekend rolls around: Abbr. |
| 34% | ALOHA | 5 | Expression of love in Kailua |
| 34% | TYS | 3 | Expressions of gratitude, in texts |
| 34% | MEH | 3 | Expression of apathy, in modern lingo |
| 34% | ODE | 3 | Expression of gratitude written in verse |
| 33% | OMG | 3 | Expression of surprise on the internet: Abbr. |
| 33% | AVE | 3 | Expression of good wishes in a meeting |
| 33% | GAGMEWITHASPOON | 15 | Expression of disgust in Valley Girl-speak |
| 33% | ZOINKS | 6 | Expression of surprise heard in Scooby-Doo series |
| 33% | SALADDAYS | 9 | Expression of youth coined in Antony and Cleopatra |
| 32% | SHADE | 5 | Subtle expression of disrespect, in slang |
| 32% | SMH | 3 | Online expression of disapproval: Abbr. |
| 32% | EEQUALSE/MCSQUARED | 18 | Expression of relativity depicted five times in this puzzle |
| 32% | WOW | 3 | Expression of awe from Owen Wilson, in a meme |
| 32% | HEADDESK | 8 | Physical expression of frustration, in modern lingo |
| 32% | SHADE | 5 | Subtle expression of contempt, in modern lingo |
| 31% | TGIF | 4 | Expression of relief at the start of the weekend: Abbr. |
| 31% | GENOME | 6 | The full set of genes in an organism |
| 31% | TGIF | 4 | Expression announcing the arrival of the weekend: Abbr. |
| 31% | OMG | 3 | Texter's expression of shock: Abbr. |
| 31% | OMG | 3 | Texter's expression of surprise: Abbr. |
| 31% | ETAL | 4 | Abbr. in a list of references |
| 31% | RRNA | 4 | Type of molecule: Abbr. |
| 31% | WOW | 3 | Expression of surprise for when you are in awe of something |
| 31% | DNA | 3 | Molecule studied in biology class: Abbr. |
| 31% | PROVOLONE | 9 | In favor of the first book?: Abbr. |
| 31% | INC | 3 | Abbr. in the back of a bus. |
| 30% | TGIF | 4 | End of week expression: Abbr. |