| 100% | JACKLEMMON | 10 | Portrayer of Jerry and Daphne in 42-Across: 2 wds. |
| 74% | TONYCURTIS | 10 | Portrayer of Joe and Josephine in 42-Across: 2 wds. |
| 59% | MARILYNMONROE | 13 | Portrayer of Sugar Kane in 42-Across: 2 wds. |
| 49% | KALEYCUOCO | 10 | Portrayer of Penny on 42-Across: 2 wds. |
| 49% | MICHELLEYEOH | 12 | Portrayer of Evelyn Wang in "Everything Everywhere All at Once" and Guanyin on "American Born Chinese": 2 wds. |
| 49% | JAMESHONG | 9 | Portrayer of Gong Gong in "Everything Everywhere All at Once" and Jade Emperor on "American Born Chinese": 2 wds. |
| 49% | STEPHANIEHSU | 12 | Portrayer of Joy Wang in "Everything Everywhere All at Once" and Shiji Niangniang on "American Born Chinese": 2 wds. |
| 49% | LESLIENIELSEN | 13 | Portrayer of President Baxter Harris in "Scary Movie 3" and "Scary Movie 4": 2 wds. |
| 48% | MORGANFREEMAN | 13 | Portrayer of 52-Across in 15-Across: 2 wds. |
| 48% | JOHNNYGALECKI | 13 | Portrayer of Leonard Hofstadter on 42-Across: 2 wds. |
| 48% | JIMPARSONS | 10 | Portrayer of Sheldon Cooper on 42-Across: 2 wds. |
| 48% | SMOKEYROBINSON | 14 | 42-Across singer/songwriter who was inducted into the Rock and Roll Hall of Fame in 1987 (2 wds.) |
| 48% | JULIANNEMOORE | 13 | Portrayer of 14-Across' spouse in "The Kids Are All Right": 2 wds. |
| 47% | VANPELT | 7 | Last name of Linus and Lucy in 44-Across: 2 wds. |
| 46% | SANDRABULLOCK | 13 | Portrayer of bus passenger Annie Porter in "Speed": 2 wds. |
| 46% | KEANUREEVES | 11 | Portrayer of LAPD officer Jack Traven in "Speed": 2 wds. |
| 46% | MORGANFREEMAN | 13 | Portrayer of Nelson Mandela in "Invictus": 2 wds. |
| 45% | INGRIDBERGMAN | 13 | Portrayer of Humphrey Bogart's former lover in 40-Across: 2 wds. |
| 45% | ZACHARYQUINTO | 13 | Portrayer of Spock in "Star Trek Beyond": 2 wds. |
| 45% | SIMONPEGG | 9 | Portrayer of Scotty in "Star Trek Beyond": 2 wds. |
| 45% | MICHAELKEATON | 13 | Portrayer of President John Mackenzie in "First Daughter": 2 wds. |
| 45% | MORGANFREEMAN | 13 | Portrayer of President Tom Beck in "Deep Impact": 2 wds. |
| 45% | WILLIAMHOLDEN | 13 | Portrayer of screenwriter Joe Gillis in "Sunset Boulevard": 2 wds. |
| 44% | JACKNICHOLSON | 13 | Portrayer of the Joker in the 1989 film "Batman": 2 wds. |
| 44% | BRUCECAMPBELL | 13 | Portrayer of Ash Williams in "Ash vs Evil Dead": 2 wds. |
| 44% | LUCYLAWLESS | 11 | Portrayer of Ruby Knowby in "Ash vs Evil Dead": 2 wds. |
| 44% | KEVINKLINE | 10 | Portrayer of Otto West in "A Fish Called Wanda": 2 wds. |
| 44% | JEFFDANIELS | 11 | Portrayer of Jack's partner Harry Temple in "Speed": 2 wds. |
| 44% | GARYOLDMAN | 10 | Portrayer of Dracula in "Bram Stoker's Dracula" (1992): 2 wds. |
| 44% | WILLIAMSADLER | 13 | Portrayer of Colonel Stuart, the villain in "Die Hard 2": 2 wds. |