| 100% | YES | 3 | Possible response in Twenty Questions |
| 87% | YES | 3 | Possible response in the game Twenty Questions |
| 72% | ONEWORD | 7 | Like the responses in Twenty Questions |
| 64% | NOS | 3 | Some responses in the game Twenty Questions |
| 54% | NOS | 3 | Twenty Questions responses |
| 52% | YES | 3 | One of two answers in Twenty Questions |
| 51% | NOS | 3 | Some Twenty Questions responses |
| 48% | IDID | 4 | Possible response to "Who left dishes in the sink?" |
| 47% | AREYOU | 6 | Question in response to "I am" |
| 46% | AMI | 3 | Question in response to an insult, maybe |
| 46% | NOSIR | 5 | One possible response to general questions? |
| 45% | ANSWERS | 7 | Solutions given in response to questions |
| 45% | ARENTI | 6 | Smug question in response to praise |
| 45% | YESNO | 5 | Like the questions in Twenty Questions: Hyph. |
| 45% | YESNO | 5 | Like questions asked in Twenty Questions: Hyph. |
| 44% | SOON | 4 | Response to the question in 38-Across |
| 44% | HOWSOON | 7 | Question in response to "I need this in a hurry" |
| 44% | NEWPHONEWHODIS | 14 | Snarky text in response to an unwanted question |
| 43% | THISOLDTHING | 12 | Question asked modestly in response to "That looks great on you" |
| 41% | PLEA | 4 | What a defendant enters in response to a judge's question |
| 39% | WHATSSOFUNNY | 12 | Question asked in response to the starts of both words in 20-, 28- and 48-Across |
| 38% | ANIMAL | 6 | Twenty questions category |
| 38% | GUESS | 5 | Twenty questions attempt |
| 38% | YES | 3 | Twenty Questions answer |
| 38% | MINERAL | 7 | Twenty Questions category |
| 38% | YES | 3 | Twenty Questions reply |
| 38% | VEGETABLE | 9 | Twenty Questions category |
| 38% | PLEA | 4 | Response in court |
| 38% | INTHISECONOMY | 13 | Jokey question in response to a statement that may have nothing to do with money |
| 37% | TTYL | 4 | Possible response to "cya" |