| 100% | AMBI | 4 | Prefix with "dextrous" to mean someone who uses both left and right hand with equal ease |
| 51% | AMBI | 4 | Prefix with "dextrous" to mean skilled at using both hands |
| 44% | AMBI | 4 | Prefix with "dextrous" to mean equally adept with both hands |
| 43% | AMBI | 4 | Prefix with "dextrous" for someone that can use both hands equally well |
| 41% | NAY | 3 | Prefix with "sayer" to mean someone who is always criticizing |
| 41% | UNI | 3 | Prefix with "sex" to mean suitable for both male and female |
| 40% | SOUL | 4 | Prefix with "mate" to mean someone who is the perfect match for you |
| 37% | SHOWY | 5 | A word used to describe someone who is flamboyant and theatrical (rhymes with "snowy") |
| 36% | SWITCHHITTER | 12 | Term for 14-Across, a player who's able to bat both right- and left-handed: Hyph. |
| 35% | EER | 3 | Suffix with "auction" to mean someone who conducts auctions |
| 35% | ARD | 3 | Suffix with "drunk" to mean someone who is habitually drunk |
| 34% | LESS | 4 | Suffix with "home" to mean someone who doesn't have one |
| 34% | THENHL | 6 | Org. with both left- and right-wingers |
| 34% | PRE | 3 | Prefix used with "historic" to mean primitive |
| 33% | NEAR | 4 | Prefix with "sighted" to mean someone that cannot see far away objects |
| 33% | BIO | 3 | Prefix used with "data" to mean a resume |
| 33% | OMNI | 4 | Prefix used with "potent" to mean all-powerful |
| 33% | PER | 3 | Prefix used with "cent" to mean "for every hundred" |
| 32% | AERO | 4 | Prefix with "space" to collectively mean the atmosphere and outer space |
| 32% | SEMI | 4 | Prefix with a meaning akin to "hemi-" and "demi-" |
| 31% | ALT | 3 | Key to both the left and right of a PC's space bar |
| 31% | PERI | 4 | Prefix with "scope," used to mean an instrument used in submarines |
| 31% | CALLACAB | 8 | Advice to someone who's drunk and about to leave |
| 30% | PROPER | 6 | *According to etiquette ... or a word used with 42d to mean very formal and well-behaved |
| 30% | RANT | 4 | *Go on a tirade ... or a word used with 25d to mean shout and complain angrily |
| 30% | OMNI | 4 | Prefix with present to mean ubiquitous |
| 30% | AGRI | 4 | Prefix with culture to mean farming |
| 30% | MACRO | 5 | Prefix with economics to mean "large" |
| 30% | ANGST | 5 | Feeling for someone who's not at ease with [waves hands] all this |
| 30% | GEO | 3 | Prefix with science to mean Earth science |