| 100% | TOR | 3 | Primary publishing imprint of Tom Doherty Associates with the slogan "Science fiction. Fantasy. The universe. And related subjects." |
| 31% | WRINKLEINTIME | 13 | With "A," classic science fantasy novel, and a feature of the theme answers |
| 30% | NEBULA | 6 | Annual award presented by the Science Fiction and Fantasy Writers of America |
| 30% | BRANDON | 7 | With 40-Across, science fiction and fantasy writer known for the series "Mistborn," "The Reckoners," and 10-Across |
| 29% | NEBULA | 6 | ___ Award, prize given to the best works of science fiction or fantasy published in the U.S. |
| 29% | KURTVONNEGUT | 12 | American novelist in the Science Fiction and Fantasy Hall of Fame who was born in 1922 (2 wds.) |
| 28% | GOVAN | 5 | Area of Glasgow formerly associated with the weaving, coal and shipbuilding industries |
| 28% | ARTHURCCLARKE | 13 | "2001: A Space Odyssey" novelist who was inducted into the Science Fiction and Fantasy Hall of Fame in 1997 (3 wds.) |
| 27% | KATEWILHELM | 11 | "The Mile-Long Spaceship" short-story writer who was inducted into the Science Fiction and Fantasy Hall of Fame in 2003 (2 wds.) |
| 27% | RAYBRADBURY | 11 | "S Is for Space" short-story writer who was inducted into the Science Fiction and Fantasy Hall of Fame in 1999 (2 wds.) |
| 27% | UNESCO | 6 | Agcy. with the slogan “Building peace in the minds of men and women” |
| 27% | THREELITTLEPIGS | 15 | Homeowners associated with the ends of 17-, 28- and 43-Across |
| 27% | COSMOLOGY | 9 | The science related to the origin of the universe |
| 27% | TENNIS | 6 | With 41-Across, question associated with the last words of 17-, 26-, 55- and 64-Across |
| 27% | WOODY | 5 | With 63-Across, name associated with the starts of 17-, 23-, 36-, 45- and 57-Across |
| 26% | BILLY | 5 | Name associated with the starts of 17-, 27-, 48- and 64-Across |
| 26% | COCOCHANEL | 10 | Fashion designer associated with the item spelled out by the starts of 17-, 26- and 42-Across |
| 26% | JUNO | 4 | Goddess of womanhood and childbirth associated with the Greek Hera by the Romans |
| 26% | WWE | 3 | Sports entertainment company associated with the likes of Yokozuna and Hulk Hogan: Abbr. |
| 26% | JAFFA | 5 | Ancient port in Israel associated with the mythological story of Andromeda and Perseus |
| 26% | THEBIGBADWOLF | 13 | Fairy tale villain associated with the ends of 20-, 27- and 49-Across |
| 26% | ANAT | 4 | Subject dealing with the structure of humans and animals, for short |
| 26% | CLUE | 4 | Game associated with the starts of 17-, 23-, 32-, 40-, 47- and 54-Across |
| 26% | CLAY | 4 | Potter's material associated with the end of 17-, 27-, 49- and 64-Across |
| 26% | SCI | 3 | Subject with the periodic table and the laws of motion, for short |
| 26% | YESWECAN | 8 | Campaign slogan associated with a Chicago politician of the 2000s |
| 26% | NOSE | 4 | Part of the body associated with sneezing, sniffling and snoring |
| 26% | OLDMACDONALD | 12 | Subject of a children's song associated with the vowels in the answer to each starred clue |
| 26% | CLARKE | 6 | Arthur C —, author of science fiction novels The Sands of Mars and Prelude to Space |
| 25% | KENTON | 6 | Stan —, US composer and pianist associated with the big band progressive jazz style of the 1950s |