| 100% | JIMLOVELL | 9 | Real-life astronaut played by Tom Hanks in "Apollo 13": 2 wds. |
| 70% | CHARLIEWILSON | 13 | Real-life congressman played by Tom Hanks in a 2007 movie: 2 wds. |
| 68% | BENBRADLEE | 10 | Real-life newspaper editor played by Tom Hanks in "The Post": 2 wds. |
| 65% | FREDROGERS | 10 | Real-life children's entertainer played by Tom Hanks in a 2019 movie: 2 wds. |
| 64% | WALTDISNEY | 10 | Real-life Oscar-winning animator played by Tom Hanks in a 2013 movie: 2 wds. |
| 64% | TOMPARKER | 9 | Real-life talent manager and "Colonel" played by Tom Hanks in "Elvis": 2 wds. |
| 63% | WALTDISNEY | 10 | Real-life animator and film producer played by Tom Hanks in "Saving Mr. Banks": 2 wds. |
| 63% | JIM | 3 | Astronaut Lovell who was played by Tom Hanks in "Apollo 13" |
| 60% | CHARLIEWILSON | 13 | Title role played by Tom Hanks in a 2007 comedy-drama: 2 wds. |
| 60% | LARRYCROWNE | 11 | Title role played by Tom Hanks in a 2011 romantic comedy: 2 wds. |
| 59% | FORRESTGUMP | 11 | Title role played by Tom Hanks in a 1994 Oscar-winning movie: 2 wds. |
| 57% | WALTDISNEY | 10 | Animation pioneer played by Tom Hanks in "Saving Mr. Banks" (2 wds.) |
| 56% | BENBRADLEE | 10 | Newspaper editor played by Tom Hanks in "The Post" (2 wds.) |
| 55% | MISTERROGERS | 12 | TV host played by Tom Hanks in "A Beautiful Day in the Neighborhood" (2 wds.) |
| 54% | FREDHAISE | 9 | Astronaut played by Bill Paxton in Apollo 13 |
| 53% | MEHRANKARIMI | 12 | Actor Tom Hanks's character in 2004 comedy-drama "The Terminal" which was inspired by a real-life person named ___ Nasseri: 2 wds. |
| 52% | RONWOODROOF | 11 | The real life character played by Matthew McConaughey in the Oscar winning movie "Dallas Buyers Club": 2 wds. |
| 52% | GREGSHORT | 9 | Character played by Colin Hanks in "Life in Pieces": 2 wds. |
| 49% | ANTHONYNELSON | 13 | Astronaut played by Larry Hagman in "I Dream of Jeannie": 2 wds. |
| 46% | ETHANHUNT | 9 | Fictional spy played by Tom Cruise in "Mission: Impossible" film series: 2 wds. |
| 45% | JAMESBDONOVAN | 13 | Actor Tom Hanks's character in 2005 historical drama "Bridge of Spies" which was inspired by a real-life lawyer named ___: 3 wds. |
| 45% | TOMHANKS | 8 | "Sully" actor who played real-life astronaut Jim Lovell in the 1995 film "Apollo 13": 2 wds. |
| 44% | COMMANDERLOVELL | 15 | Tom Hanks, in Apollo 13 |
| 44% | HOWARDHUGHES | 12 | Real-life business magnate played by Leonardo DiCaprio in 2004's "The Aviator": 2 wds. |
| 43% | ICHABODCRANE | 12 | Hero of 13-Across, played by Tom Mison: 2 wds. |
| 42% | FORRESTGUMP | 11 | Tom Hanks' 1994 drama film based on a Winston Groom novel of the same name in which 20a plays his love interest: 2 wds. |
| 41% | KEVINBACON | 10 | "Footloose" actor who plays astronaut Jack Swigert in "Apollo 13" (2 wds.) |
| 41% | BILLPAXTON | 10 | "Twister" actor who plays astronaut Fred Haise in "Apollo 13" (2 wds.) |
| 41% | JORDANBELFORT | 13 | Real-life stock market manipulator played by Leonardo DiCaprio in 2013's "The Wolf of Wall Street": 2 wds. |
| 41% | GEORGEBAILEY | 12 | Character played by 29-Across in "It's a Wonderful Life" (2 wds.) |