| 100% | JEDGARHOOVER | 12 | Real-life FBI director and title character played by Leonardo DiCaprio in a 2011 film: 3 wds. |
| 45% | VIWARSHAWSKI | 12 | Title detective played by Kathleen Turner in a 1991 film: 3 wds. |
| 39% | GREENLANTERN | 12 | Superhero played by Ryan Reynolds in a 2011 film (2 wds.) |
| 38% | LARRYCROWNE | 11 | Title role played by Tom Hanks in a 2011 romantic comedy: 2 wds. |
| 38% | JANEEYRE | 8 | Literary governess played by Mia Wasikowska in a 2011 film (2 wds.) |
| 38% | HOWARDHUGHES | 12 | Real-life business magnate played by Leonardo DiCaprio in 2004's "The Aviator": 2 wds. |
| 38% | KILLERJOE | 9 | Title hit man played by Matthew McConaughey in a 2011 film |
| 37% | JORDANBELFORT | 13 | Real-life stock market manipulator played by Leonardo DiCaprio in 2013's "The Wolf of Wall Street": 2 wds. |
| 37% | GEORGEBAILEY | 12 | Character played by 29-Across in "It's a Wonderful Life" (2 wds.) |
| 36% | CRUELLADEVIL | 12 | Character played by Emma Stone in the 2021 Disney film featuring dalmatians: 3 wds. |
| 34% | ANDOR | 5 | Title character played by Diego Luna in a "Star Wars" TV series |
| 34% | EYRE | 4 | Literary title character played by Wasikowska in 2011 |
| 34% | ALLMYCHILDREN | 13 | Long-running daytime drama featuring the wedding of the characters played by real-life couple 15-Across and 27-Across (3 wds.) |
| 34% | COSMOKRAMER | 11 | Character played by Michael Richards in "Seinfeld", who is 32-Across's neighbor and is often called a "hipster doofus": 2 wds. |
| 33% | AMELIE | 6 | Title character played by Audrey Tautou in a quirky 2002 Oscar-nominated French rom-com |
| 33% | LOLITA | 6 | Character played by Sue Lyon in a 1962 Stanley Kubrick film |
| 33% | LADYMACBETH | 11 | Scheming spouse played by Jeanette Nolan, Alex Kingston, and Marion Cotillard in film versions of a Shakespeare play (2 wds.) |
| 33% | JESSEPINKMAN | 12 | Character played by Aaron Paul in "Breaking Bad", who was a crystal meth dealer and worked with the character played by 30-Across: 2 wds. |
| 33% | ROMEO | 5 | Role played by Leonardo DiCaprio on film and Orlando Bloom on stage |
| 33% | COSMOKRAMER | 11 | Character played by Michael Richards in a sitcom about "nothing" (2 wds.) |
| 33% | EYRE | 4 | Governess Jane played by Mia Wasikowska in a 2011 film |
| 33% | BILBOBAGGINS | 12 | Character played by 27-Across in "The Hobbit" films (2 wds.) |
| 32% | RONWOODROOF | 11 | The real life character played by Matthew McConaughey in the Oscar winning movie "Dallas Buyers Club": 2 wds. |
| 32% | MARIEANTOINETTE | 15 | Title queen played by Kirsten Dunst in a 2006 Sofia Coppola film |
| 32% | CAMEO | 5 | Small character played by an A-lister in a film |
| 32% | GLORIASTEINEM | 13 | Feminist journalist played by 15-Across and Alicia Vikander in a 2020 biopic based on the memoir "My Life on the Road" (2 wds.) |
| 32% | ELAINEBENES | 11 | Character played by Julia Louis-Dreyfus in a sitcom about "nothing" (2 wds.) |
| 32% | CHARLIEWILSON | 13 | Title role played by Tom Hanks in a 2007 comedy-drama: 2 wds. |
| 32% | THEGRINCH | 9 | Title villain played by Jim Carrey in a 2000 Christmas movie (2 wds.) |
| 32% | WALTDISNEY | 10 | Real-life animator and film producer played by Tom Hanks in "Saving Mr. Banks": 2 wds. |