| 100% | TESSMONAGHAN | 12 | Reporter-turned-investigator in a series of crime novels by 44-Across (2 wds.) |
| 82% | TESSMONAGHAN | 12 | Reporter-turned-investigator in a series of novels by 44-Across (2 wds.) |
| 57% | ARMANDGAMACHE | 13 | Chief inspector in a series of mystery novels by Louise Penny (2 wds.) |
| 57% | EVEDUNCAN | 9 | Forensic sculptor in a series of novels by Iris Johansen (2 wds.) |
| 56% | DARKOFTHEMOON | 13 | First book in a series of novels by John Sandford featuring 46-Across (4 wds.) |
| 56% | CORKOCONNOR | 11 | Former small-town sheriff featured in a series of novels by William Kent Krueger, including "Iron Lake," 18-Across, and 29-Across (2 wds.) |
| 55% | MYRONBOLITAR | 12 | Fictional basketball player-turned-sports agent who solves mysteries in a series of novels by 35-Across (2 wds.) |
| 51% | EARTHSEACYCLE | 13 | Series of high fantasy novels and stories by 44-Across set on an otherworldly archipelago in an uncharted ocean (2 wds.) |
| 51% | WAYSIDESCHOOL | 13 | Setting for a series of novels by 30-Across (2 wds.) |
| 48% | STRIPTEASE | 10 | Novel by 44-Across that was made into a movie starring Demi Moore: 2 wds. |
| 48% | CENTURYCYCLE | 12 | Series of 10 plays by 14-Across, including "Fences" and "The Piano Lesson," that chronicle life in Black America over a 100-year span: 2 wds. |
| 48% | RAMONATHEPEST | 13 | One in a series of books by 46-Across about a girl starting kindergarten: 3 wds. |
| 48% | THEPITTFAMILY | 13 | Household of Victorian investigators in a mystery series by novelist Anne Perry (3 wds.) |
| 48% | HENRYANDRIBSY | 13 | One in a series of books by 46-Across about a boy and his dog: 3 wds. |
| 47% | HARRYHOLE | 9 | Detective in a series of Jo Nesbø crime novels |
| 47% | ONTOUR | 6 | Performing concerts in a series of locations: 2 wds. |
| 47% | BASKETCASE | 10 | Novel by 44-Across that highlights a song by the same name cowritten with Warren Zevon: 2 wds. |
| 47% | JOHNNYENGLISH | 13 | Fictional spy portrayed by Rowan Atkinson in a series of parody films: 2 wds. |
| 47% | THESCHOLOMANCE | 14 | Trilogy of novels by 27-Across set in a magic school (2 wds.) |
| 46% | TWILIGHT | 8 | First book in a series of vampire novels by Stephenie Meyer |
| 46% | THEFALLEN | 9 | Thriller novel by David Baldacci which was part of "Memory Man" series and became a NYT 2018 Bestseller: 2 wds. |
| 46% | SHUTTERISLAND | 13 | Novel by 44-Across made into a film directed by Martin Scorsese (2 wds.) |
| 45% | THENIGHTINGALE | 14 | 2015 novel by 44-Across set in France during World War II (2 wds.) |
| 44% | WHITENOISE | 10 | Novel by 44-Across that was adapted as a 2022 film by Noah Baumbach (2 wds.) |
| 44% | CASCA | 5 | Roman soldier in a series of novels by Barry Sadler beginning with 1979's The Eternal Mercenary |
| 43% | HARRIETTUBMAN | 13 | Abolitionist and political activist played by 44-Across in a 2019 biopic (2 wds.) |
| 43% | PETERRABBIT | 11 | Animated character voiced by 44-Across in a 2018 film (2 wds.) |
| 43% | AMERICANRUST | 12 | Novel by 31-Across set in a declining Pennsylvania steel town (2 wds.) |
| 42% | GONEBABYGONE | 12 | Novel by 44-Across made into a film directed by Ben Affleck (3 wds.) |
| 42% | THEBLUESTEYE | 12 | Novel by 44-Across about an African-American girl in 1940s Ohio (3 wds.) |