| 100% | LEONARD | 7 | Robert Sean ___, actor who plays Dr. James Wilson on "House, M.D." |
| 69% | SPENCER | 7 | Jesse ___, actor who plays Dr. Robert Chase on "House, M.D." |
| 63% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 63% | OMAR | 4 | ___ Epps, actor who plays Dr. Eric Foreman on "House, M.D." |
| 52% | HUGH | 4 | ___ Laurie, actor who plays Gregory House on "House, M.D." |
| 52% | JESSESPENCER | 12 | Australian actor who played Dr Robert Chase in US television series House |
| 52% | MARKHARMON | 10 | "NCIS" actor who played Dr. Robert Caldwell on "St. Elsewhere": 2 wds. |
| 51% | OLIVERPLATT | 11 | "Huff" actor who plays Dr. Daniel Charles on "Chicago Med": 2 wds. |
| 49% | TEE | 3 | Actor Brian who plays Dr. Ethan Choi on "Chicago Med" |
| 47% | OMAR | 4 | With 39-Down, actor who plays Dr. Eric Foreman on "House" |
| 47% | LISAEDELSTEIN | 13 | Actress who plays Dr. Cuddy on "House, M.D.": 2 wds. |
| 47% | OMAR | 4 | With 38-Down, actor who played Dr. Eric Foreman on "House" |
| 47% | OWEN | 4 | Actor Wilson who plays Mobius M. Mobius on "Loki" |
| 47% | HUGHLAURIE | 10 | Actor who played Dr. Gregory House in "House" |
| 46% | OMAR | 4 | Actor Epps who plays Dr. Eric Foreman on "House" |
| 46% | OMAR | 4 | Actor Epps who played Dr. Eric Foreman on "House" |
| 45% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane on "Frasier": 2 wds. |
| 45% | WILDE | 5 | Olivia ___, actress who plays Dr. Remy on "House, M.D." |
| 44% | HUGH | 4 | Actor Laurie, who played the role of Dr. House in the show "House M.D" |
| 44% | EPPS | 4 | Omar —, actor who played Dr Eric Foreman in US television series House |
| 43% | HARRISONFORD | 12 | "1923" actor who plays Dr. Paul Rhoades on "Shrinking" (2 wds.) |
| 42% | RYANEGGOLD | 10 | "The Blacklist" actor who plays Dr. Max Goodwin on "New Amsterdam" (2 wds.) |
| 42% | OMIDABTAHI | 10 | "American Gods" actor who plays Dr. Pershing on "The Mandalorian" (2 wds.) |
| 42% | BURR | 4 | Raymond —, Canadian actor who played Perry Mason and Robert Ironside on television |
| 42% | WYLE | 4 | Actor Noah who plays Dr. Carter on "ER" |
| 41% | RAYLIOTTA | 9 | "Goodfellas" actor who plays James "Big Jim" Keene on 46-Across (2 wds.) |
| 41% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |
| 41% | ADAM | 4 | Actor Arkin who played Dr. Shutt on "Chicago Hope" |
| 41% | LUKETENNIE | 10 | "CSI: Vegas" actor who plays Sean on the Apple TV+ series "Shrinking" (2 wds.) |