| 100% | EXOMARS | 7 | Roscosmos Space Corporation and ESA's mission to search for life, recently delayed until 2022 |
| 31% | EDDINGTON | 9 | Canceled ESA mission to search for planets |
| 22% | KIRKDOUGLAS | 11 | "Lust for Life" and "Spartacus" actor who lived to be 103: 2 wds. |
| 22% | NATURALLAW | 10 | Basis for the rights to life and liberty, to John Locke |
| 21% | GROPE | 5 | To search for something blindly |
| 21% | OLE | 3 | Her s___ purpose in life was to provide for herself and her family |
| 21% | TERRAFORM | 9 | 2022 dictionary addition meaning "to change an area so it's suitable for human life" |
| 21% | SNAPPY | 6 | "Make it ___," phrase asking for something to be done quickly and without delays |
| 21% | MIA | 3 | "Go for the Goal: A Champion's Guide to Winning in Soccer and Life" author Hamm |
| 20% | TRACE | 5 | Search for and discover |
| 20% | QUESTPERMISSION | 15 | License to search for the Holy Grail? |
| 20% | IMAGE | 5 | Reverse ___ search (tool for identifying a picture ... or a hint to 12-Across and 14-Across) |
| 20% | HOME | 4 | ___ Economics, school elective subject for students who want to learn life skills like cooking and budgeting |
| 20% | NOSTONEUNTURNED | 15 | Search aim, and a hint to this puzzle's theme |
| 20% | MENSA | 5 | Gp. you could approach to search for genii |
| 19% | THEFRIENDSWEMADEALONG | 21 | With 126/127 Across, companions on our life's journey who were more valuable to us than our destination ... and an alternate title for this puzzle |
| 19% | HUNT | 4 | Search for hard nut to crack |
| 19% | MOONFALL | 8 | Halle Berry and Patrick Wilson's 2022 space film |
| 19% | CAL | 3 | Home to L.A. and S.F., for short |
| 19% | COUPONING | 9 | Searching for discount codes and bargain buys |
| 19% | ALIENLIFE | 9 | What 2023's space mission Juice is hoping to find |
| 19% | DEEPWEB | 7 | Content that's hard for a search engine to access |
| 19% | CRT | 3 | Term for which RCA held the trademark until 1951, when the corporation released its use to the public domain |
| 19% | NEWSHOLE | 8 | Paper's space available for stories as opposed to ads |
| 19% | OPERA | 5 | John Adams's 2022 work "Antony and Cleopatra," for one |
| 19% | MYSTERYMEAT | 11 | Searching for clues and interviewing suspects, e.g. |
| 19% | SET | 3 | ___ for life (never needing to work again) |
| 19% | ALIENCONTACT | 12 | ... about the search for extraterrestrial life? |
| 19% | EGGHUNT | 7 | Easter search for candies and chocolates |
| 18% | SET | 3 | ___ for life (never needing to worry about money) |