| 100% | WHOWANTSTOKNOW | 14 | Sassy question in response to a question |
| 71% | HOWSOON | 7 | Question in response to "I need this in a hurry" |
| 69% | INTHISECONOMY | 13 | Jokey question in response to a statement that may have nothing to do with money |
| 69% | PLEA | 4 | What a defendant enters in response to a judge's question |
| 62% | ANSWER | 6 | Response to a question |
| 62% | ANSWER | 6 | A response to a question |
| 62% | ANS | 3 | Response to a question: Abbr. |
| 62% | ANS | 3 | Response to a question (Abbr.) |
| 61% | AREYOU | 6 | Question in response to "I am" |
| 61% | ANS | 3 | Response to a question, for short |
| 60% | AMI | 3 | Question in response to an insult, maybe |
| 60% | BALLETANSWER | 12 | Response to a question about “Swan Lake”? |
| 59% | ARENTI | 6 | Smug question in response to praise |
| 59% | ILLGETIT | 8 | Words in response to a doorbell |
| 59% | REFLEX | 6 | Involuntary movement in response to a stimulus |
| 59% | AMEN | 4 | Word shouted in response to a pastor |
| 59% | ISTHATALL | 9 | Sassy response to a scolding |
| 59% | NOSIR | 5 | Response to a general question? |
| 58% | OLE | 3 | When repeated, cry in response to a goal |
| 58% | IDO | 3 | Response to a bailiff's question |
| 58% | HMM | 3 | Response to a thought-provoking question |
| 58% | OOF | 3 | Response to a punch, in comics |
| 58% | PLEA | 4 | Response to a charge, in court |
| 57% | FIRE | 4 | Emoji sent in response to a hot outfit pic |
| 57% | SOON | 4 | Response to the question in 38-Across |
| 57% | OOF | 3 | Response to a punch in the stomach |
| 57% | OOF | 3 | Response to a punch in the gut |
| 57% | LOL | 3 | Response to a joke in textspeak: Abbr. |
| 56% | LOL | 3 | Response to a joke in a chat room |
| 56% | LOL | 3 | Response to a joke in an I.M. |