| 100% | TRON | 4 | Sci-fi film recognized with an Oscar for Technical Achievement 15 years after it was released |
| 37% | ENYA | 4 | Singer with an Oscar nomination for "May It Be" (from the first "Lord of the Rings" film) |
| 29% | MIR | 3 | It was in orbit for 15 years |
| 28% | TRON | 4 | Pioneering sci-fi film that was snubbed for the Best Visual Effects Oscar for its use of computers |
| 28% | WATER | 5 | "Avatar: The Way of ___," 2022 sci-fi film that was in production for 12 years |
| 27% | FACE | 4 | "___/Off," 1997 sci-fi film starring John Travolta and Nicolas Cage that was nominated for an Academy Award |
| 27% | THEM | 4 | Classic 1954 sci-fi film with an exclamation point in its title |
| 26% | LAWRENCE | 8 | With 50-Across, Best Picture Oscar film released 50 years ago |
| 26% | THELAST | 7 | With 15-Across, Oscar film for '87 (with Peter O'Toole) |
| 26% | LUPITANYONGO | 12 | Actress who won an Oscar for her first feature film role, in "12 Years a Slave": 2 wds. |
| 26% | IROBOT | 6 | 1950 sci-fi fixup novel by Isaac Asimov that shares its title with a 2004 film starring Will Smith: 2 wds. |
| 26% | LANGE | 5 | Jessica with an Oscar for "Tootsie" |
| 25% | NAME | 4 | "Spell My ___ with an S," sci-fi short story by Isaac Asimov that was adapted into a 2014 short film directed by Samuel Ali |
| 25% | JURASSICPARK | 12 | Steven Spielberg's hit sci-fi film which celebrates its 25th anniversary this year and was based on a Michael Crichton novel: 2 wds. |
| 25% | JAMIE | 5 | Foxx with an Oscar for playing Ray |
| 25% | ARGO | 4 | It won the Oscar for Best Picture the year after "The Artist" |
| 25% | ALIEN | 5 | Sci-fi film with a hatching egg on its poster |
| 25% | EMMA | 4 | Stone with an Oscar for "La La Land" |
| 25% | SORVINO | 7 | Actress Mira with an Oscar for "Mighty Aphrodite" |
| 25% | EDDIE | 5 | Redmayne with an Oscar for playing Stephen Hawking |
| 25% | GAGA | 4 | Lady ___ (singer with an Oscar for Best Original Song) |
| 25% | ANG | 3 | Lee with an Oscar for "Crouching Tiger, Hidden Dragon" |
| 25% | EMMA | 4 | Actress Stone with an Oscar for "La La Land" |
| 24% | TRON | 4 | Classic sci-fi film with a sequel 28 years later |
| 24% | ALIEN | 5 | Sci-fi film with an android named Ash |
| 24% | MIRACLEWORKER | 13 | With "The," 1962 film for which 15-Across won an Oscar for portraying Helen Keller: 2 wds. |
| 24% | EAR | 3 | Body part that, after an "H" is added, becomes what you can do with it |
| 24% | SAM | 3 | Singer Smith with an Oscar for "Writing's on the Wall" |
| 24% | ALAN | 4 | Arkin with an Oscar nomination for "Argo" |
| 24% | CASTINGDIRECTOR | 15 | Film professional with an eye for talent |