| 100% | READYPLAYERONE | 14 | Science fiction novel by Ernest Cline that released in 2011 and became a NYT Bestseller again in 2018: 3 wds. |
| 38% | HOLYGHOST | 9 | Book by John Sandford which was part of the "Virgil Flowers" novel series and became a NYT 2018 Bestseller: 2 wds. |
| 38% | AROUNDTHEMOON | 13 | Science fiction novel by Jules Verne that features a lunar trip: 3 wds. |
| 38% | THEFALLEN | 9 | Thriller novel by David Baldacci which was part of "Memory Man" series and became a NYT 2018 Bestseller: 2 wds. |
| 32% | INACROWN | 8 | "You Should See Me ___," Billie Eilish song released in 2018 and the title of which was inspired by a scene from "Sherlock": 3 wds. |
| 31% | LETSMAKELOVE | 12 | Duet by Faith Hill and Tim McGraw, released in 2000, that won the couple a Grammy for Best Country Collaboration with Vocals: 3 wds. |
| 30% | OLDMAN | 6 | *"The ___ and the Sea," 1952 novel by Ernest Hemingway that was adapted into a 1958 film: 2 wds. |
| 30% | ISLAND | 6 | "The ___ of Doctor Moreau," 1896 science fiction novel by H.G. Wells that follows a scientist and his hybrid creations |
| 30% | READYPLAYERONE | 14 | Steven Spielberg film based on a 2011 Ernest Cline novel: 3 wds. |
| 30% | THESONGOF | 9 | With 24-Across, 2011 Madeline Miller novel that became a 2021 hit thanks to TikTok: 3 wds. |
| 29% | THISISAMERICA | 13 | Childish Gambino's superhit song released in 2018 that addresses issues of gun violence and racism: 3 wds. |
| 29% | WALKONBY | 8 | Song by Burt Bacharach and 26-Across that was a hit for 15-Across in 1964: 3 wds. |
| 29% | JEDGARHOOVER | 12 | Real-life FBI director and title character played by Leonardo DiCaprio in a 2011 film: 3 wds. |
| 28% | BREAKINGDAWN | 12 | Fourth and final novel in "The Twilight Saga" which was released as a two part movie in 2011: 2 wds. |
| 28% | STATEOFWONDER | 13 | 2011 novel by 28-Across that was shortlisted for the Orange Prize for Fiction (3 wds.) |
| 28% | ONESWEETDAY | 11 | Song by 42-Across and Boyz II Men that spent a record 16 weeks at #1 in 1995-1996: 3 wds. |
| 27% | THEROUNDHOUSE | 13 | 2012 Novel by 44-Across that won a National Book Award for Fiction (3 wds.) |
| 27% | THEOLDMAN | 9 | "___ and the Sea," a 1999 Academy award-winning animated short film based on Ernest Hemingway's novel by the same name: 3 wds. |
| 27% | TOTHEFUTURE | 11 | "Back ___," 1985 science fiction film in which the protagonist travels back in time and accidentally becomes his mother's romantic interest: 3 wds. |
| 27% | THELIONKING | 11 | Animated film released in 1994 which was influenced by Shakespeare's "Hamlet" and tells the story of a character named Simba: 3 wds. |
| 27% | THEWITCHELM | 11 | 2018 novel by Tana French whose central mystery involves a skull found in a tree (3 wds.) |
| 27% | APAINTEDHOUSE | 13 | Novel by John Grisham which was made into a television film starring Scott Glenn in 2003: 3 wds. |
| 27% | MAN | 3 | "The Invisible ___," 1897 science fiction novel by H.G. Wells that follows a scientist named Griffin |
| 27% | THEGIANTPEACH | 13 | "James and ___," children's novel written by Roald Dahl in 1961, about a young boy's adventure with seven magically-altered garden bugs: 3 wds. |
| 26% | GAMEOFTHRONES | 13 | Drama that has featured Kit Harington and Rose Leslie, who married in 2018: 3 wds. |
| 26% | THEXFACTOR | 10 | Music competition series created by Simon Cowell that featured 53-Across as a host in 2012 and 2013 (3 wds.) |
| 26% | COMET | 5 | "Off On A ___," science fiction novel by Jules Verne about characters that are unwittingly carried off into space |
| 26% | THEOVERSTORY | 12 | 2018 novel by 32-Across that won the Pulitzer Prize for Fiction (2 wds.) |
| 26% | READYPLAYERONE | 14 | Movie based on a 2011 Ernest Cline book: 3 wds. |
| 26% | WOMENTALKING | 12 | Novel by 36-Across about an isolated Mennonite community in Bolivia that was adapted by 17-Across into a film starring Frances McDormand, Claire Foy, and Rooney Mara (2 wds.) |