| 100% | EINSTEIN | 8 | Scientist who developed the theory of relativity |
| 82% | EINSTEIN | 8 | Scientist who espoused the theory of relativity |
| 79% | ALBERTEINSTEIN | 14 | Physicist who developed the theory of relativity: 2 wds. |
| 66% | DARWIN | 6 | Charles who developed the theory of evolution |
| 61% | EINSTEIN | 8 | The man who discovered the theory of relativity |
| 61% | PASCAL | 6 | Blaise —, 17th-century mathematician and philosopher who developed the theory of probability with Pierre de Fermat |
| 54% | STAHL | 5 | Georg Ernst —, German scientist born in 1659 who developed the phlogiston theory of combustion |
| 52% | EDDINGTON | 9 | First Englishman to prove the Theory of Relativity |
| 49% | NEWTON | 6 | Scientist who developed three "laws of motion" |
| 49% | EINSTEIN | 8 | Father of the theory of relativity |
| 47% | EDDIE | 5 | With 50-Across, "The Theory of Everything" actor who plays weather scientist James Glaisher in 30-Across |
| 47% | ULM | 3 | Where Einstein, who conceived the General Theory of Relativity, was himself conceived |
| 47% | CHEMIST | 7 | Scientist who studies the transformations and reactions of substances |
| 46% | ASIMOV | 6 | I, Robot sci-fi author who developed the Three Laws of Robotics |
| 46% | GEODESISTS | 10 | Scientists who measure the exact shape and size of Earth |
| 46% | HOFFMAN | 7 | German chemist who developed the use of aspirin |
| 46% | NEWTON | 6 | Famous scientist who formulated the laws of motion |
| 46% | EINSTEIN | 8 | Physicist Albert who came up with the special theory of relativity |
| 45% | CORIOLIS | 8 | Eponymous scientist who studied the behavior of moving bodies |
| 45% | BOHR | 4 | Physics Nobelist who developed an early model of the atom |
| 45% | VEBLEN | 6 | Economist who wrote "The Theory of the Leisure Class" |
| 43% | MARIECURIE | 10 | Scientist who was the first female professor at the University of Paris: 2 wds. |
| 43% | BROCA | 5 | Scientist for whom a part of the brain is named |
| 43% | DAVIDGRAEBER | 12 | Anthropologist who developed the concept of everyday communism in “Debt: The First 5,000 Years” |
| 43% | SALK | 4 | Scientist who was called the "Father of Biophilosophy" in the New York Times in 1966 |
| 41% | GRACE | 5 | ___ Hopper, computer scientist who was honored with the Presidential Medal of Freedom posthumously in 2016 |
| 41% | EULER | 5 | Mathematician who wrote the first theorem of graph theory |
| 41% | ISAAC | 5 | Scientist ___ Newton who discovered the laws of gravity |
| 41% | EMC | 3 | Letters in Einstein's theory of relativity |
| 41% | MASS | 4 | Quantity in Einstein's theory of relativity |