| 100% | SHAGGY | 6 | Scooby Doo's owner and best friend |
| 48% | PHINEAS | 7 | Ferb's stepbrother and best friend |
| 47% | DAPHNE | 6 | Scooby Doo's orange-haired mystery-solving friend |
| 44% | SHAGGY | 6 | Scooby-Doo's owner |
| 43% | EPITHETS | 8 | "Man's best friend" and "The Terrible" |
| 42% | ANN | 3 | Leslie's best friend on "Parks and Recreation" |
| 42% | SHAGGY | 6 | Scooby's human best friend |
| 42% | SHAGGY | 6 | Scooby-Doo's scruffy owner |
| 41% | SHAGGY | 6 | Scooby-Doo's human best buddy |
| 41% | GRANGER | 7 | Best friend of Potter and Weasley |
| 41% | SHAGGY | 6 | Scooby-Doo's long-haired friend |
| 41% | RON | 3 | Good friend of Harry and Hermione |
| 40% | DAPHNE | 6 | Friend of Velma, Shaggy and Scooby-Doo |
| 40% | ISLA | 4 | Scooby Doo and Wedding Crashers actress Fisher |
| 40% | LENA | 4 | Best friend of Carmen, Bridget and Tibby |
| 40% | KOOMSON | 7 | Dorothy —, author of novels My Best Friend's Girl and The Ice Cream Girls |
| 40% | GUS | 3 | Cinderella's helper and Jaq's best mouse friend |
| 40% | CHIENPO | 7 | Best friend of Yao and Ling in Mulan |
| 39% | MELANIE | 7 | Scarlett's sister-in-law and best friend in "Gone With the Wind" |
| 38% | NALA | 4 | Simba's childhood best friend and eventual wife in "The Lion King" |
| 38% | GRACE | 5 | Will's best friend on an American sitcom starring Eric McCormack and Debra Messing |
| 38% | SHIRLEY | 7 | Laverne's best friend in the 1970s sitcom starring Penny Marshall and Cindy Williams |
| 38% | ARF | 3 | Scooby Doo's bark |
| 37% | DAPHNE | 6 | "Scooby-Doo" friend of Velma, Fred and Shaggy |
| 37% | HANNA | 5 | Scooby Doo's co-creator |
| 37% | SHAGGY | 6 | Scooby Doo's human companion |
| 37% | STAR | 4 | Patrick ___, SpongeBob's best friend and neighbor in the animated TV series, "SpongeBob SquarePants" |
| 37% | RON | 3 | Harry and Hermione's best friend at Hogwarts |
| 36% | GREATDANE | 9 | Scooby Doo's giant dog breed |
| 36% | ALPO | 4 | Best friend's dinner, maybe |