| 100% | HARRISONFORD | 12 | Second actor to play the CIA operative played by Chris Pine in "Jack Ryan: Shadow Recruit" (2 wds.) |
| 46% | LYLEWAGGONER | 12 | Actor who first played Steve Trevor, the pilot played by Chris Pine in the new "Wonder Woman" films (2 wds.) |
| 45% | WILLIAMSHATNER | 14 | Actor who first played James T. Kirk, the captain played by Chris Pine in the new "Star Trek" films (2 wds.) |
| 38% | PETERCAPALDI | 12 | Twelfth actor to play the lead role in 15-Across, starting in 2013: 2 wds. |
| 38% | MATTSMITH | 9 | Eleventh actor to play the lead role in 15-Across (2010-2013): 2 wds. |
| 38% | DAVIDTENNANT | 12 | Tenth actor to play the lead role in 15-Across (2005-2010): 2 wds. |
| 38% | THECOMPANY | 10 | Three-part series about the activities of the CIA during the Cold War in which Chris O'Donnell plays Jack McAuliffe: 2 wds. |
| 37% | ALECBALDWIN | 11 | Actor who made a cameo in "Glengarry Glen Ross" by playing the role of Blake, the guy who is sent to motivate the sales team: 2 wds. |
| 37% | LEONARDNIMOY | 12 | Actor who meets his younger self, played by Zachary Quinto, in the 2009 film "Star Trek": 2 wds. |
| 36% | PINE | 4 | Chris ___, "Wonder Woman" star who played Jack Ryan in "Jack Ryan: Shadow Recruit" |
| 36% | BRUCEWILLIS | 11 | Actor who meets his younger self, played by Joseph Gordon-Levitt, in the 2012 film "Looper": 2 wds. |
| 36% | COREYFELDMAN | 12 | "Stand by Me" actor who played the Petersons' neighbor, Ricky Butler, in 50-Across: 2 wds. |
| 36% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 35% | KYLECHANDLER | 12 | "Manchester by the Sea" actor who plays Brooks in "Game Night": 2 wds. |
| 35% | SCOTTGLENN | 10 | Actor who plays Jack Crawford in the 1991 psychological thriller film, "The Silence of the Lambs": 2 wds. |
| 35% | RIVERPHOENIX | 12 | "My Own Private Idaho" actor who played Chris in "Stand by Me": 2 wds. |
| 35% | NICKKROLL | 9 | "Big Mouth" actor who plays recurring character Simon the Devious in "What We Do in the Shadows": 2 wds. |
| 35% | DOUGJONES | 9 | "Star Trek: Discovery" actor who plays recurring character Baron Afanas in "What We Do in the Shadows": 2 wds. |
| 35% | BURTREYNOLDS | 12 | "Smokey and the Bandit" actor who played filmmaker Jack Horner in "Boogie Nights": 2 wds. |
| 35% | CHANNINGTATUM | 13 | "Magic Mike" actor who plays the novelist's cover model trying to rescue her in "The Lost City": 2 wds. |
| 35% | WHITEYWINN | 10 | Character played by actor Thomas Brodie-Sangster in the hit Netflix television drama mini-series "Godless": 2 wds. |
| 34% | BRYANCRANSTON | 13 | Actor who plays Walter White in "Breaking Bad", the protagonist who also goes by the name Heisenberg: 2 wds. |
| 34% | DEANJONES | 9 | "The Love Bug" actor who played Wilby Daniels as an adult in the sequel to 29-Across: 2 wds. |
| 34% | JACKRYAN | 8 | CIA politico played by a Baldwin brother, Harrison Ford, Ben Affleck, and Chris Pine (2 wds.) |
| 34% | DWAYNEJOHNSON | 13 | Actor who plays Dr. Smolder Bravestone in "Jumanji: Welcome to the Jungle" (2 wds.) |
| 34% | JOSHTAYLOR | 10 | Actor who joined the cast of "Days of Our Lives" in 1977 as Chris Kositchek and later started playing Roman Brady: 2 wds. |
| 34% | TOMCRUISE | 9 | Actor who plays Jack Reacher in the "Jack Reacher" films (2 wds.) |
| 34% | ROBINWRIGHT | 11 | Actor from "Forrest Gump", who plays the wife of the character played by 18-Across in "House of Cards": 2 wds. |
| 34% | COREYHAIM | 9 | "License to Drive" actor who played younger brother Sam in the 1987 vampire movie "The Lost Boys": 2 wds. |
| 33% | JACKNICHOLSON | 13 | Actor who played Jack Torrance in the 1980 film "The Shining" (2 wds.) |