| 100% | JAVIERBAEZ | 10 | Second baseman acquired by the Mets from the Cubs before the 2021 trade deadline: 2 wds. |
| 84% | ANTHONYRIZZO | 12 | First baseman acquired by the Yankees from the Cubs before the 2021 trade deadline: 2 wds. |
| 84% | KRISBRYANT | 10 | Third baseman acquired by the Giants from the Cubs before the 2021 trade deadline: 2 wds. |
| 36% | BENZOBRIST | 10 | Cubs second baseman who started the 2016 MLB All-Star Game: 2 wds. |
| 35% | JACKIEROBINSON | 14 | Trailblazing Dodgers second baseman posthumously awarded the Presidential Medal of Freedom by Ronald Reagan: 2 wds. |
| 34% | BLINDINGLIGHTS | 14 | 2020 hit by The Weeknd, the second single from 16-Across: 2 wds. |
| 33% | RYNESANDBERG | 12 | Cubs second baseman, inducted into the Hall of Fame in 2005, who became the Phillies' manager in 2013: 2 wds. |
| 32% | THEHILLS | 8 | Single by The Weeknd from his second album which made a record in the Billboard Hot R&B chart : 2 wds. |
| 31% | JACKANTONOFF | 12 | Lorde's "Green Light" from her second album was co-written by ___, lead guitarist of the indie rock band "Fun": 2 wds. |
| 31% | ITBE | 4 | "Let ___," final song from The Beatles before McCartney announced his departure: 2 wds. |
| 30% | BLANKSPACE | 10 | Second single from Taylor Swift's fifth album, that received three Grammy nominations, and had a part in the lyrics misheard by many: 2 wds. |
| 30% | PETEALONSO | 10 | New York Mets first baseman who won the 2021 Home Run Derby (2 wds.) |
| 30% | WONTBACKDOWN | 12 | "I ___," 1989 song by Tom Petty from the album "Full Moon Fever": 2 wds. |
| 30% | PRIVATEDANCER | 13 | 1984 song by Tina Turner from her album of the same name: 2 wds. |
| 30% | ROBINSONCANO | 12 | Seattle Mariners second baseman who won the 2017 MLB All-Star Game MVP: 2 wds. |
| 29% | JOSEALTUVE | 10 | Houston Astros second baseman who was the Associated Press Athlete of the Year in 2017: 2 wds. |
| 29% | DUSTINPEDROIA | 13 | Red Sox second baseman who was the 2007 AL Rookie of the Year & 2008 AL MVP: 2 wds. |
| 29% | TAKEMYBREATH | 12 | 2021 hit by The Weeknd, and the lead single from "Dawn FM": 3 wds. |
| 29% | KILLTHENOISE | 12 | Single by Papa Roach from the album "Ego Trip" that reached #1 on the "Billboard" Mainstream Rock Songs chart in 2021 (2 wds.) |
| 29% | KRISBRYANT | 10 | Cubs third baseman who was the 2015 NL Rookie of the Year & 2016 NL MVP: 2 wds. |
| 29% | JOSEALTUVE | 10 | Houston Astros second baseman who won the AL Hank Aaron Award in 2017: 2 wds. |
| 29% | TUFFJUICE | 9 | "___: My Journey from the Streets to the NBA," an autobiography by Caron Butler: 2 wds. |
| 29% | CIAAGENT | 8 | Job held by the four characters from 15-, 19-, 31-, and 40-Across: 2 wds. |
| 29% | ANTHONYRIZZO | 12 | Cubs first baseman who started the 2016 MLB All-Star Game: 2 wds. |
| 29% | KRISBRYANT | 10 | Cubs third baseman who started the 2016 MLB All-Star Game: 2 wds. |
| 29% | CORPUSCHRISTI | 13 | "Miss ___," the title won by 18a before she moved to Hollywood: 2 wds. |
| 29% | LUCASSCOTT | 10 | The primary protagonist from "One Tree Hill," played by 30-Across: 2 wds. |
| 28% | KEITHMOON | 9 | English drummer rated second-greatest drummer by Rolling Stone who was part of the band "The Who": 2 wds. |
| 28% | ROBINSONCANO | 12 | New York Yankees second baseman who was named MVP of the 2013 World Baseball Classic: 2 wds. |
| 28% | JIMHALPERT | 10 | A character from "The Office" played by John Krasinski, who eventually marries the receptionist Pam: 2 wds |