| 100% | THRESH | 6 | Separate the seeds from |
| 94% | GAN | 3 | Separate the seeds from cotton |
| 64% | MEN | 3 | Separate the ___ from the boys |
| 64% | CHAFF | 5 | Separate the wheat from the ___ |
| 63% | THRESH | 6 | Separate the wheat from the chaff |
| 63% | THRESH | 6 | Separate the grain from the chaff |
| 62% | GINS | 4 | Cotton ___ (machines that remove the seeds from certain plants) |
| 61% | THRESH | 6 | Separate seed from |
| 61% | THRESHED | 8 | Separated seed from |
| 60% | CHIA | 4 | Tiny seeds from the mint family |
| 58% | ALASKAPENINSULA | 15 | It separates the Bering Sea from the Pacific |
| 58% | GINNED | 6 | Separated cotton from seeds by machine |
| 58% | REMOT/VE | 8 | Separate from all the others, say |
| 58% | UNDOCKS | 7 | Separates from the mother ship, say |
| 57% | CURB | 4 | It separates the street from the sidewalk |
| 57% | AGEGAP | 6 | What separates the men from the boys? |
| 57% | AGE | 3 | What separates the men from the boys |
| 57% | ISOLATE | 7 | Keep separate from the rest |
| 56% | CHIA | 4 | Healthy smoothie seed from the mint family (anagram of "chai") |
| 56% | ORCHID | 6 | The world's smallest seeds come from one |
| 56% | ADRIATIC | 8 | Sea separating the Balkans from the Italian peninsula |
| 55% | ADRIATIC | 8 | Sea separating Italy from the Balkans |
| 55% | WHEAT | 5 | It's separated from the chaff |
| 54% | LAGOONS | 7 | Shallow waters partly separated from the sea |
| 54% | ADRIATIC | 8 | Sea separating Italy from the Balkan Peninsula |
| 54% | CHAFF | 5 | Mass of husks separated from seeds during threshing |
| 53% | MALESORTER | 10 | That which separates the men from the boys? |
| 53% | HORIZON | 7 | Line that separates the sky from the earth |
| 53% | STRAITOFMESSINA | 15 | It separates Sicily from the rest of Italy |
| 53% | WIDEOUT | 7 | Pass receiver somewhat separated from the offensive line |