| 100% | COUNTERSTRIKE | 13 | Series of first-person shooter video games whose latest instalment is "Global Offensive" : Hyph. |
| 41% | HALO | 4 | Video game series whose first installment was subtitled "Combat Evolved" |
| 36% | MYST | 4 | 1990s video game whose first sequel was Riven |
| 36% | COUNTERSTRIKE | 13 | Multiplayer first-person shooter video game published by Valve in which terrorists battle counter-terrorists: Hyph. |
| 35% | HALO | 4 | Video game series whose protagonist is Master Chief |
| 35% | STUMBLE | 7 | *___ Guys, online video game whose title is a synonym of 1a |
| 34% | HALO | 4 | Video game franchise whose first game is subtitled "Combat Evolved" |
| 34% | HALO | 4 | First-person shooter video game franchise |
| 33% | ANIMALCROSSING | 14 | Video game series whose 2020 "New Horizons" game was a big hit: 2 wds. |
| 33% | HALO | 4 | First-person shooter video game franchise featuring Master Chief |
| 33% | PERSON | 6 | Call of Duty is a first ___ shooter game |
| 33% | HALO | 4 | Popular first-person shooter video game |
| 32% | TOPEKA | 6 | Capital whose last two letters are the first two letters of its state |
| 32% | VERMONT | 7 | State whose last four letters are the first four letters of its capital |
| 32% | HEROSDUTY | 9 | First-person shooter video game in 20-Across: 2 wds. |
| 32% | HALO | 4 | Popular first-person shooter video game since 2001 |
| 32% | KONG | 4 | Donkey ___, series of video games first released in 1981 and which has a gorilla character |
| 31% | DOOM | 4 | First-person shooter game released in 1993 by id Software which is considered to be one of the most influential video games of all time |
| 31% | FIFA | 4 | Soccer organization's video game series that was first released in 1993 by EA Sports: Abbr. |
| 31% | COLECO | 6 | Old video game company whose first four letters match the middle four letters of 115 Across |
| 31% | GEHRIG | 6 | First baseman Lou whose record of consecutive games was broken by Cal Ripken Jr. |
| 31% | LADO | 4 | Director Aldo whose first name is an anagram of his last name |
| 31% | MYST | 4 | Video game whose sequel was Riven |
| 31% | RIPTORN | 7 | Entertainer whose last name is the past tense of a synonym of his first name |
| 31% | KRIS | 4 | Singer whose first name is the first four letters of his last name |
| 31% | HALO | 4 | Sci-fi first-person shooter video game franchise |
| 30% | NBA | 3 | "___ Jam," long-running basketball organization's video game series that was first released in 1993 by Midway: Abbr. |
| 30% | HALO | 4 | First-person shooter game involving an alliance of aliens known as Covenant |
| 30% | SIMS | 4 | Virtual people in a series of video games |