| 100% | EDEN | 4 | Setting for Genesis 2:8-25 |
| 56% | EDEN | 4 | Genesis 2 setting |
| 54% | GOTHAMCITY | 10 | Setting for "Batman": 2 wds. |
| 53% | MEAN | 4 | 5, for the set {2, 4, 6, 8} |
| 53% | MEAN | 4 | 5, for the set [2, 4, 6, 8] |
| 50% | KENT | 4 | Setting for part of "King Henry VI, Part 2" |
| 50% | EVEN | 4 | 2, 8 or 10, for e.g. |
| 48% | FOODCOURT | 9 | Legal setting for 17-, 25-, 45- and 53-Across? |
| 48% | FIRSTGEAR | 9 | Stick-shift setting for very low speeds: 2 wds. |
| 48% | CUBEROOTS | 9 | 2 for 8, 3 for 27, etc. |
| 48% | AGOAL | 5 | Set ___ (plan for an accomplishment): 2 wds. |
| 46% | ADDED | 5 | Solved 2 + 4 + 6 + 8, for example |
| 46% | PST | 3 | Setting for the '25 Oscars |
| 46% | OLDWEST | 7 | Setting for "Deadwood" (2 wds.) |
| 46% | COMICBOOK | 9 | Setting for each of the places in 15-, 21-, and 41-Across: 2 wds. |
| 45% | WILDWEST | 8 | Setting for horse operas (2 wds.) |
| 44% | TENNISCOURT | 11 | Lorde song named for an athletic setting: 2 wds. |
| 44% | CHICAGOCUBS | 11 | Team for which 25-/35-Across played: 2 wds. |
| 44% | EDEN | 4 | Garden first named in Genesis 2:8 |
| 44% | EDEN | 4 | Place first named in Genesis 2:8 |
| 43% | NESTEGGS | 8 | Funds that are set aside for the future: 2 wds. |
| 43% | OLDWEST | 7 | Setting for some Clint Eastwood movies (2 wds.) |
| 43% | PROMOCODE | 9 | Set of numbers and/or letters entered for an online discount: 2 wds. |
| 42% | CRIMELAB | 8 | Setting for many "Bones" and "CSI" scenes (2 wds.) |
| 42% | PLAYMONEY | 9 | Cash in a Monopoly set, for example: 2 wds. |
| 42% | ELMST | 5 | Setting for a horror film franchise, for short (2 wds.) |
| 41% | OAHUHAWAII | 10 | Island setting for "Magnum, P.I." (2 wds.) |
| 41% | PLANON | 6 | Set aside time for (2 wds.) |
| 41% | ARLENEFRANCIS | 13 | She was a regular panelist on 18-Across for 25 years: 2 wds. |
| 41% | WAYSIDESCHOOL | 13 | Setting for a series of novels by 30-Across (2 wds.) |