| 100% | HELICES | 7 | Shapes studied by Dr. Watson and his partner |
| 44% | DNA | 3 | Material studied by Watson and Crick |
| 36% | BATCAVE | 7 | Headquarters for Robin and his partner |
| 34% | POLIO | 5 | Disease studied by Salk and Sabin |
| 32% | GRAVITY | 7 | Phenomenon studied by Galileo, Newton and Einstein |
| 32% | SCIENCE | 7 | Field studied by Newton, Franklin and Hawking |
| 32% | ECONOMICS | 9 | Discipline studied by Keynes, Friedman, and Smith |
| 32% | ELS | 3 | Shapes made by thumbs and index fingers |
| 31% | PEROT | 5 | His companies were bought by GM and Dell |
| 31% | ROLEX | 5 | Brand worn by Dr. King and Jay-Z |
| 31% | ASSTS | 5 | Igor and Dr. Watson: Abbr. |
| 31% | WAKEUPBABE | 10 | Words on a meme depicting a man and his sleeping partner |
| 31% | ELL | 3 | Shape formed by an extended thumb and index fingers |
| 31% | ROUNDWORM | 9 | Parasite studied by winners Campbell and Omura |
| 30% | XERS | 4 | Jay-Z and Dr. Dre, by birth |
| 30% | OBLONG | 6 | Like kiwis and plum tomatoes, by shape |
| 30% | STEAM | 5 | "Mike Mulligan and His ___ Shovel" (classic kids' book by Virginia Lee Burton) |
| 30% | WIFE | 4 | "The Fisherman and His ___," German fairy tale collected by the Brothers Grimm |
| 30% | AFRO | 4 | Hairstyle worn by Dr. J during his basketball career |
| 30% | APE | 3 | Animal studied by Jane Goodall and Dian Fossey |
| 30% | WAVERLEY | 8 | Novel by Walter Scott and his literary collection |
| 30% | NEFARIO | 7 | Gru's inventor and partner-in-crime: Dr. __ |
| 30% | TOPOLOGICAL | 11 | Relating to the study of shapes and surfaces |
| 30% | TWO | 3 | "___ Old Broads" (book about aging by Dr. M.E. Hecht and Whoopi Goldberg) |
| 29% | SPIDERMAN | 9 | Superhero raised by his Uncle Ben and Aunt May |
| 29% | SCARLET | 7 | A Study in __, tale where Holmes and Watson meet |
| 29% | PLASTIC | 7 | __ art, 3-D forms created by modeling and shaping |
| 29% | BASKIN | 6 | His partner had a cone-shaped pool |
| 29% | ANGEL | 5 | Shape made by flapping one's arms and legs in the snow |
| 29% | ABEL | 4 | Son of Adam and Eve killed by his brother Cain |