| 100% | SHERYLSWOOPES | 13 | She was the first player signed by a WNBA team: 2 wds. |
| 56% | SHERYLSWOOPES | 13 | Basketball Hall of Fame inductee who was the first player to sign with the WNBA: 2 wds. |
| 55% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 54% | SHERYLSWOOPES | 13 | Openly gay basketballer who was the first woman to be signed by the WNBA: 2 wds. |
| 53% | CYNTHIACOOPER | 13 | She was the first WNBA MVP: 2 wds. |
| 44% | LEADOFF | 7 | Be the first baseball player to bat: 2 wds. |
| 44% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 42% | SHOHEIOHTANI | 12 | Japanese MLB player who was the first player in history to be a pitcher and hitter in the All-Star Game, in 2021: 2 wds. |
| 41% | LOUGEHRIG | 9 | His #4 was the first number ever retired by Major League Baseball (Yankees, 1939): 2 wds. |
| 41% | LORENAOCHOA | 11 | She was the first Mexican golfer to rank #1 in the world and received golf's Bob Jones Award in 2011: 2 wds. |
| 40% | BRITTNEYGRINER | 14 | First player to dunk twice in a WNBA game: 2 wds. |
| 39% | STELLAMARIS | 11 | 2022 prequel to "The Passenger" that is the first novel by 34-Across to feature a female protagonist (2 wds.) |
| 39% | ETHELWATERS | 11 | Harlem Renaissance singer and actress who was the first African American to star in her own TV show: 2 wds. |
| 39% | LUKEAIKINS | 10 | American skydiver who was the first to land safely without a parachute or wingsuit from mid-tropospheric altitude: 2 wds. |
| 39% | HOUSTONCOMETS | 13 | WNBA team that won the league's first four championships (2 wds.) |
| 39% | RICKEYJACKSON | 13 | Former American Football linebacker (birthday today) who was the first Saints player elected to Pro Football Hall of Fame: 2 wds. |
| 39% | TONIMORRISON | 12 | "Beloved" author who died August 5, and who was the first African-American woman to win a Nobel Prize: 2 wds. |
| 38% | WAYNEGRETZKY | 12 | Hockey legend who was the first since Bobby Orr to tally 100+ assists in a season, and did so 11 times: 2 wds. |
| 37% | VALACKERMAN | 11 | 2021 Basketball Hall of Fame inductee who was the first president of the WNBA (2 wds.) |
| 37% | ALTHEAGIBSON | 12 | Tennis great who was the first person of color to win a Wimbledon championship (2 wds.) |
| 37% | SARAHPALIN | 10 | In 2006, she became the first woman to be elected governor of Alaska: 2 wds. |
| 37% | GWENJORGENSEN | 13 | American distance runner and two-time ITU World Champion who was the first to win a triathlon gold for USA in the Olympics: 2 wds. |
| 37% | REGGIEMILLER | 12 | Shaquille and ___ were the only two players in both the gold medal-winning national teams of 1994 and 1996: 2 wds. |
| 37% | AVADUVERNAY | 11 | "Selma" director who was the first African-American woman nominated for a Best Picture Oscar (2 wds.) |
| 37% | SUSANAMARTINEZ | 14 | In 2010, she became the first woman to be elected governor of New Mexico: 2 wds. |
| 37% | NIKKIHALEY | 10 | In 2010, she became the first woman to be elected governor of South Carolina: 2 wds. |
| 37% | MARIOLEMIEUX | 12 | Penguins center who was the third player to have a 100-assist season: 2 wds. |
| 37% | MYRTLEWILSON | 12 | She is killed in a hit-and-run accident in "The Great Gatsby": 2 wds. |
| 37% | HANKGREENBERG | 13 | Detroit Tigers slugger who was the first player named MLB MVP for two different fielding positions (outfield and first base) (2 wds.) |
| 37% | INAWE | 5 | "He was ___ of her from the first day" (bowled over) : 2 wds. |