| 100% | ENOLAHOLMES | 11 | Sherlock’s sleuthing sister, in a 2020 film |
| 64% | ENOLA | 5 | Sherlock's sister, per a 2020 Netflix film |
| 59% | ENOLA | 5 | Sherlock's younger sister in a YA book series |
| 57% | NOMAD | 5 | Frances McDormand plays one in a 2020 film |
| 56% | AVA | 3 | Title assassin in a 2020 film |
| 55% | ENOLA | 5 | Sherlock's sister in a book series |
| 55% | ENOLA | 5 | Sherlock's sister in a YA book series |
| 54% | EMMA | 4 | Jane Austen title heroine in a 2020 film adaptation |
| 53% | ENOLA | 5 | Sherlock's sister in a book series by Nancy Springer |
| 53% | TESLA | 5 | Inventor Nikola played by Ethan Hawke in a 2020 film |
| 52% | ENOLA | 5 | Sherlock Holmes's younger sister in a series of YA novels |
| 52% | EMMA | 4 | Jane Austen matchmaker played by Anya Taylor-Joy in a 2020 film |
| 51% | SONIC | 5 | Video game character in a hit 2020 film |
| 51% | ROBERTDOWNEYJR | 14 | "Iron Man" actor who plays 53-Across in a 2020 film (3 wds.) |
| 51% | ANYATAYLORJOY | 13 | "Glass" actress who played 19-Across in a 2020 film: 2 wds., hyph. |
| 51% | ROBERTDOWNEYJR | 14 | "Iron Man" actor who played Doctor Dolittle in a 2020 film: 3 wds. |
| 50% | ANYATAYLORJOY | 13 | "Split" and "Glass" actress who plays 43-Across in a 2020 film (3 wds.) |
| 50% | EMMA | 4 | Jane Austen title heroine played by Anya Taylor-Joy in a 2020 film adaptation |
| 50% | MULAN | 5 | Title role for Yifei Liu in a 2020 Disney film |
| 50% | EMMA | 4 | 1815 classic whose title character is played by Anya Taylor-Joy in a 2020 film |
| 48% | GRETEL | 6 | Sister in a children's story |
| 48% | ENOLA | 5 | "___ Holmes" (2020 film about Sherlock's sister) |
| 46% | ENOLA | 5 | Sherlock and Mycroft’s sister, in a Nancy Springer series |
| 45% | MILO | 4 | Title cat in a 1980's cartoon film |
| 45% | NINEDAYS | 8 | Titular length of the interview process for souls waiting to be born, in a 2020 Edson Oda film |
| 45% | DUKE | 4 | "The ___," 2020 film starring Jim Broadbent that has a royal designation in its title |
| 44% | NOMAD | 5 | Lead-in to "land" in a hit 2020 film |
| 44% | PALM | 4 | "___ Springs," 2020 film starring Andy Samberg as a wedding guest stuck in a time loop |
| 44% | NUN | 3 | Sister in a convent |
| 44% | NUN | 3 | Sister in a habit |