| 100% | JOLT | 4 | Shock to the system |
| 82% | EYEOPENER | 9 | Shock to the system, and what the start of each answer to a starred clue can be |
| 69% | TRAUMA | 6 | Shock to the body |
| 63% | PACEMAKER | 9 | Device that sends electrical shocks to the heart |
| 62% | ELECTRIC | 8 | Defibrillation is an __ shock to the chest or heart |
| 60% | PENAL | 5 | Relating to the criminal justice system |
| 60% | NEURO | 5 | Prefix relating to the nervous system |
| 60% | PENAL | 5 | Related to the criminal-justice system |
| 59% | ODE | 3 | "___ to the Female Reproductive System" (Sharon Olds poem) |
| 59% | NEUROLOGY | 9 | Medical science related to the nervous system |
| 58% | GAMED | 5 | ___ the system (manipulated the rules to one's advantage) |
| 57% | BOHRATOM | 8 | Physics model using an analogy to the solar system |
| 57% | WAY | 3 | Milky ___ (galaxy that's home to the solar system) |
| 56% | MARS | 4 | Home to the largest known volcano in the solar system |
| 56% | DEEPSKY | 7 | Outside the solar system, to astronomers |
| 54% | SPACESHIP | 9 | Vehicle used to travel the solar system |
| 54% | IMAC | 4 | Computer that may have recently updated to the Big Sur operating system |
| 53% | MARS | 4 | Planet next to Earth in the solar system |
| 53% | IGNITION | 8 | Electrical system, sparks fuel to start the engine |
| 52% | MARS | 4 | Red planet next to Earth in the Solar System |
| 51% | AHCA | 4 | Bill that promises to overhaul the medical system, for short |
| 50% | WEBSEARCH | 9 | "___ Engine," software system to find things on the Internet: 2 wds. |
| 50% | WRECKITRALPH | 12 | Command to consumer advocate Nader to destroy the computer systems department? |
| 49% | ABELINCOLN | 10 | Political leader who patented a system to alter the buoyancy of steamboats |
| 48% | ACOL | 4 | Popular British bridge bidding system that started to evolve in the mid-1930s |
| 48% | ABMHO | 5 | Unit of electrical conductance in the emu-cgs system, equal to 109 siemens |
| 48% | INPUT | 5 | Enter into the system |
| 48% | HILT | 4 | To the ___ |
| 48% | MAX | 3 | To the ___ |
| 47% | GPS | 3 | Navigational system involving satellites used to determine the position of a receiver on Earth |