| 100% | RHIMES | 6 | Shonda __, creator of Grey's Anatomy and Scandal |
| 63% | SHONDARHIMES | 12 | Creator of "Grey's Anatomy" and "Scandal" … or, when said aloud, a hint to the starts of 20-, 30 and 45-Across |
| 60% | SHONDARHIMES | 12 | Creator/writer of the TV series "Grey's Anatomy" and "Scandal" (2 wds.) |
| 57% | SHONDA | 6 | Grey's Anatomy and Bridgerton creator Rhimes |
| 53% | YES | 3 | "Year of ___" (memoir by "Grey's Anatomy" creator Shonda Rhimes) |
| 49% | RHIMES | 6 | "Grey's Anatomy" creator Shonda |
| 47% | SHONDARHIMES | 12 | Grey's Anatomy writer and producer ... and a punny description of the starts to 20-, 28-, and 43-Across |
| 46% | SHONDA | 6 | With 34-Across, creator and producer of "Grey's Anatomy" |
| 46% | SANDRAOH | 8 | Grey's Anatomy and Killing Eve actor |
| 45% | SHONDA | 6 | Rhimes who created "Grey's Anatomy" and "Scandal" |
| 45% | SHONDALAND | 10 | Production company for “Grey’s Anatomy” and “Scandal” |
| 44% | ALLEN | 5 | Debbie of "Fame" and "Grey's Anatomy" |
| 43% | SHONDA | 6 | Producer Rhimes who created "Grey's Anatomy" and "Scandal" |
| 43% | DEMPSEY | 7 | Grey's Anatomy co-star of Pompeo |
| 42% | SHONDARHIMES | 12 | TV producer behind "Grey's Anatomy" and "Scandal": 2 wds. |
| 41% | MEREDITH | 8 | Dr. Grey of “Grey’s Anatomy” |
| 41% | BACARDI | 7 | Owner of Grey Goose and Dewar's |
| 39% | STAT | 4 | "I am on Grey's Anatomy, and this is urgent!" |
| 38% | ELLEN | 5 | Pompeo of ''Grey's Anatomy'' |
| 38% | HEIGL | 5 | Katherine of ''Grey's Anatomy'' |
| 38% | POMPEO | 6 | Ellen of “Grey’s Anatomy” |
| 38% | MILNE | 5 | Creator of Rabbit and Piglet |
| 38% | ERLE | 4 | Creator of Perry and Della |
| 38% | MILNE | 5 | Creator of Pooh and Piglet |
| 38% | WALT | 4 | Creator of Mickey and Minnie |
| 38% | NEIL | 4 | Creator of Felix and Oscar |
| 38% | DOYLE | 5 | Creator of Holmes and Watson |
| 38% | IAN | 3 | Creator of Q and M |
| 38% | TWAIN | 5 | Creator of Finn and Sawyer |
| 38% | TWAIN | 5 | Creator of Sawyer and Finn |