| 100% | CSI | 3 | Show that had episodes titled "Tressed to Kill" and "Dead of the Class" |
| 44% | NUDE | 4 | Second single from Radiohead's album in 18a, that had a different title originally and was supposed to be part of the album "OK Computer" |
| 39% | COLD | 4 | ___ open, term and scene that is shown before the title song of a TV show |
| 37% | INLIVINGCOLOR | 13 | Sketch comedy show that launched Jim Carrey and Jennifer Lopez, and a hint to the titles in 17-, 28-, 44- and 60-Across |
| 37% | WISEACRE | 8 | Word that comes from the Dutch for "soothsayer" and, despite appearances, has no relation to a unit of measurement |
| 37% | AMPHIBIA | 8 | The class of animals that includes frogs and newts |
| 36% | RETINA | 6 | Part of the eye that has rods and cones |
| 36% | AGT | 3 | NBC's entertainment show that has Simon Cowell as one of the judges: Abbr. |
| 36% | CMAS | 4 | Award show that has named Garth Brooks Entertainer of the Year six times, briefly |
| 36% | SNL | 3 | Show that launched the careers of Adam Sandler and Eddie Murphy: Abbr. |
| 36% | PLL | 3 | Show that follows the lives of Aria, Spencer, Hanna, and Emily: Abbr. |
| 35% | GALWAY | 6 | "___ Girl," song by English singer Ed Sheeran which has the name of an Irish city in its title that is home to Eyre Square |
| 35% | SNL | 3 | Show that was the source of "The Blues Brothers" and "Wayne's World": Abbr. |
| 35% | VIEIRA | 6 | Meredith of the "Today" show and "Who Wants to Be a Millionaire" |
| 35% | REDS | 4 | Team that has retired the numbers of Johnny Bench and Pete Rose |
| 34% | ISOTONIC | 8 | Word applied to sports drinks that have similar concentrations of salt and sugar as the human body |
| 34% | NAACP | 5 | Org. that has awarded the Spingarn Medal to Rosa Parks and Gordon Parks |
| 34% | GNU | 3 | Variation of the wildebeest that has a beard, mane and a sloping back |
| 34% | SPINE | 5 | Part of a book that often shows the title |
| 34% | ELSA | 4 | Baby name that had popularity bumps after the releases of "Frozen" and "Frozen II" |
| 34% | UNESCO | 6 | Agency of the United Nations that sponsors programmes to promote education and the arts |
| 34% | NONSTARTER | 10 | Plan that has no chance of working ___ or the answer to each starred clue? |
| 34% | NONSTARTER | 10 | Plan that has no chance of working ... or the answer to each starred clue? |
| 34% | LIVE | 4 | "Saturday Night ___," American late night variety show that had LeBron James as the host of the season 33 premiere |
| 33% | CAPTAIN | 7 | Title that can precede the starts of 17-, 23-, 49- and 59-Across |
| 33% | FINALE | 6 | Term used to describe the last episode of a TV show |
| 33% | HITCOUNTERS | 11 | Widgets that show the number of visitors to a Web site |
| 33% | NERVE | 5 | Bundle of fibers that transmits impulses to and from the brain |
| 33% | VOODOO | 6 | Type of doll that Singh tries to kill Indy with in "Indiana Jones and the Temple of Doom" |
| 33% | SNL | 3 | NBC sketch show that added Chloe Fineman and Bowen Yang to the cast in 2019 (Abbr.) |