| 100% | VEEP | 4 | Show whose title character likened her job to being “sealed in an abandoned coal mine under two miles of human shit” |
| 28% | BARETTA | 7 | Nineteen-seventies cop show whose title character was a master of disguise |
| 25% | HEDDAGABLER | 11 | Henrik Ibsen play whose title character manipulates others in order to fulfill her own desires: 2 wds. |
| 25% | SURVEYOR | 8 | Someone whose job is to examine an area of land |
| 25% | QUEEN | 5 | ___ of Hearts, "Alice in Wonderland" character whose name is connected to 13a |
| 25% | FRANFINE | 8 | Title character of 15-Across, whose first name is shared by actress Drescher who plays her: 2 wds. |
| 24% | AGORAHILLS | 10 | 2023 Doja Cat hit whose title is a tribute to a town she lived in: 2 wds. |
| 24% | DAD | 3 | "American ___!" (animated show whose title character is Stan Smith) |
| 24% | CALVIN | 6 | Comics title character who says "Getting an inch of snow is like winning 10 cents in the lottery" |
| 24% | FLEABAG | 7 | 2019 Emmy-winning show in which the title character is never referred to by her name |
| 23% | ALF | 3 | 1980s sitcom whose title character was an alien |
| 23% | TOSCA | 5 | Puccini opera whose title character is an opera singer |
| 23% | BREAKINGBAD | 11 | AMC show whose title is stylized with two chemical symbols |
| 23% | PARISTROUT | 10 | Pete Dexter novel whose title character is an unrepentant murderer |
| 23% | NABUCCO | 7 | Giuseppe Verdi opera composed in 1841 whose title character is king of Babylon |
| 22% | IGOR | 4 | Animated 2008 film whose title character wants to become an evil scientist |
| 22% | DIANARIGG | 9 | "Game of Thrones" actress whose "On Her Majesty's Secret Service" character is the second to marry 16-Across (2 wds.) |
| 22% | PROMETHEUSBOUND | 15 | Ancient Greek work whose title character gives humans the power to burn things |
| 22% | ASEATATTHETABLE | 15 | 2016 Solange album, whose title is an invitation to listen |
| 22% | ARS | 3 | ___ Magna (Latin book whose title is an anagram of anagrams) |
| 22% | EREWHON | 7 | 1872 utopian novel whose title is an anagram of NOWHERE |
| 22% | ALF | 3 | Title TV character whose name is an acronym |
| 22% | EMMA | 4 | 1815 classic whose title character is played by Anya Taylor-Joy in a 2020 film |
| 22% | POSTMANPAT | 10 | BBC TV children's series whose title character works in the fictional village of Greendale |
| 22% | GALWAY | 6 | "___ Girl," song by English singer Ed Sheeran which has the name of an Irish city in its title that is home to Eyre Square |
| 22% | VEEP | 4 | Show whose main character's autobiography was titled A Woman First: First Woman |
| 21% | THEGIFT | 7 | Cate Blanchett film whose title refers to her character's clairvoyance |
| 21% | ANNA | 4 | Title character of literature in a love triangle with two 66-Across named Alexei |
| 21% | IRIS | 4 | Song by Goo Goo Dolls whose title is part of an eye |
| 21% | MANUGINOBILI | 12 | NBA star from Argentina who is one of only two players to win a EuroLeague title, an NBA championship, and an Olympic gold medal (2 wds.) |