| 100% | REBA | 4 | Sitcom about the Hart family |
| 75% | ROSEANNE | 8 | Sitcom about the Conner family |
| 66% | FAMILYGUY | 9 | Animated sitcom about the Griffin family |
| 66% | ROSEANNE | 8 | Old sitcom about the Conner family |
| 61% | ROSEANNE | 8 | John Goodman US sitcom about the Conner family |
| 61% | BLESSTHISMESS | 13 | Sitcom about the Levine-Young family starring Ed Begley Jr., Lake Bell, and 42-Across (3 wds.) |
| 60% | WARATHOME | 9 | 2005-07 sitcom about the Gold family, with "The" |
| 58% | ROSEANNE | 8 | ABC's sitcom about the fictional Conner family for which Amy Sherman-Palladino contributed as a staff writer |
| 57% | FAMILYMATTERS | 13 | 1989 American sitcom about the Winslow family living in Chicago starring Jaleel White: 2 wds. |
| 56% | SMALLWONDER | 11 | 1985 American sci-fi sitcom about the family of an engineer who creates a human girl-robot Vicki: 2 wds. |
| 54% | JETSONS | 7 | "The ___," animated sitcom produced by Hanna-Barbera which is about a family in the future |
| 54% | REBA | 4 | Hart family sitcom |
| 54% | BLACKISH | 8 | ABC sitcom about the Johnsons |
| 54% | FAMILYGUY | 9 | Animated sitcom about the Griffins |
| 53% | GOLDBERGS | 9 | TV sitcom about the 1980s, The __ |
| 53% | ROSEANNE | 8 | 1980s-'90s sitcom about the Conners |
| 51% | BIGBANG | 7 | Sitcom about geeky scientists, The __ Theory |
| 50% | FAMILYGUY | 9 | Animated Fox sitcom about the dysfunctional Griffins: 2 wds. |
| 50% | MUNSTERS | 8 | Sitcom about Frankenstein and vampire wife, The __ |
| 49% | THEGOODPLACE | 12 | NBC sitcom about the afterlife that starred Ted Danson: 3 wds. |
| 48% | THECROWN | 8 | Netflix drama about the British royal family |
| 48% | BOAT | 4 | "Fresh off the ___" (ABC sitcom about an Asian-American family) |
| 47% | SHAMELESS | 9 | TV show about the working-class Gallagher family |
| 47% | THECROWN | 8 | Netflix TV show about the British royal family |
| 47% | FAREWELL | 8 | The __, Awkwafina film about family ties |
| 47% | ALL | 3 | 1970s sitcom "___ in the Family" |
| 47% | ALF | 3 | 1980s sitcom about a creature from the planet Melmac |
| 46% | GOLDBERGS | 9 | The __, family sitcom set in 1980s Jenkintown |
| 46% | EDDIEHUANG | 10 | Chef whose memoir about growing up in a Taiwanese-American family in Florida inspired the ABC sitcom "Fresh off the Boat" (2 wds.) |
| 46% | ALL | 3 | "___ in the Family" (1970s sitcom) |