| 100% | BLESSTHISMESS | 13 | Sitcom about the Levine-Young family starring Ed Begley Jr., Lake Bell, and 42-Across (3 wds.) |
| 39% | THEOTHERTWO | 11 | HBO Max comedy starring 16-Across and 28-Across about a family dealing with the sudden fame of a younger sibling (3 wds.) |
| 36% | THEGOODPLACE | 12 | NBC sitcom about the afterlife that starred Ted Danson: 3 wds. |
| 35% | FAMILYMATTERS | 13 | 1989 American sitcom about the Winslow family living in Chicago starring Jaleel White: 2 wds. |
| 33% | PARENTHOOD | 10 | Dramedy about the Braverman family starring Peter Krause, Lauren Graham, and 42-Across |
| 33% | MODERNFAMILY | 12 | A TV show about the Pritchett and Dunphy family, in which Sofia Vergara stars: 2 wds. |
| 31% | PARKSANDREC | 11 | 2009-2015 sitcom about small-town government that featured the characters 18-Across, 24-Across, and 33-Across, for short (3 wds.) |
| 31% | SAVINGMRBANKS | 13 | 2013 film about the making of 33-Across starring Emma Thompson as 18-Across and Tom Hanks as Walt Disney (3 wds.) |
| 31% | THEUNICORN | 10 | CBS sitcom starring 18-Across and 33-Across about a recently widowed father who re-enters the dating scene (2 wds.) |
| 29% | BROADCITY | 9 | Sitcom about Abbi and Ilana in the Big Apple: 2 wds. |
| 28% | CITYOFLIES | 10 | 2018 film starring 18-Across and 34-Across about rappers Tupac Shakur and The Notorious B.I.G. (3 wds.) |
| 28% | THEGOODPLACE | 12 | 2016-2020 NBC afterlife sitcom starring Kristen Bell and Ted Danson: 3 wds. |
| 28% | BRIGHTLIGHTS | 12 | HBO documentary about the mother-daughter relationship of 32- and 42-Across: 2 wds. |
| 28% | DOWNTONABBEY | 12 | PBS "Masterpiece" series about the Earl of Grantham and his family: 2 wds. |
| 28% | SPEAKNOEVIL | 11 | 2024 horror-thriller starring 19-Across and 34-Across about a family visiting friends at their British estate (3 wds.) |
| 28% | THEODDCOUPLE | 12 | 1970-1975 sitcom about a slob and a neatnik who lived together: 3 wds. |
| 28% | DOWNTONABBEY | 12 | 2011-2015 "Masterpiece" drama about the Crawley family and their household staff: 2 wds. |
| 27% | ROCK | 4 | "30 ___," satirical sitcom about the behind the scenes of a live sketch comedy show created by and starring Tina Fey |
| 27% | SMALLWONDER | 11 | 1985 American sci-fi sitcom about the family of an engineer who creates a human girl-robot Vicki: 2 wds. |
| 27% | CRADLEOFLOVE | 12 | 42-Across hit song that was covered by Alvin and the Chipmunks in 1991 (3 wds.) |
| 27% | REBA | 4 | Sitcom about the Hart family |
| 27% | ROSEANNE | 8 | Sitcom about the Conner family |
| 27% | AINTTOOPROUD | 12 | Tony-nominated jukebox musical about the life and times of 34-Across: 3 wds. |
| 26% | THELASTDANCE | 12 | 2020 sports documentary about the 18-Across and 30-Across (3 wds.) |
| 26% | RAMONATHEPEST | 13 | 1968 novel by 38-Across about the Quimby family (3 wds.) |
| 26% | HENRYANDRIBSY | 13 | 1954 novel by 38-Across about the Huggins family (3 wds.) |
| 26% | BIGBANGTHEORY | 13 | CBS sitcom about geeky roommates, with "The": 3 wds. |
| 26% | PETERGRIFFIN | 12 | The main character and father of the family in the American sitcom, "Family Guy": 2 wds. |
| 26% | SINGLEPARENTS | 13 | ABC sitcom about divorced moms and dads starring 18-Across and 41-Across (2 wds.) |
| 26% | PAINHUSTLERS | 12 | Netflix crime drama about the pharmaceutical industry starring Emily Blunt and 31-Across (2 wds.) |