| 100% | VEEP | 4 | Sitcom in which the main character's political party is never identified |
| 45% | THEMERCHANTOF | 13 | "___ Venice," romantic comedy by Shakespeare in which the main characters are Antonio and Portia: 3 wds. |
| 44% | EVITA | 5 | Hit 1979 musical in which a character's mistress is one of the main roles |
| 43% | SHADESOFGREY | 12 | "Fifty ___," erotic novel trilogy written by E.L. James in which the main characters are Christian Grey and Ana Steele: 3 wds. |
| 39% | MACAW | 5 | The main character in "Rio" is one |
| 39% | ORFF | 4 | Composer of Der Mond, an opera in which the main characters steal the moon |
| 39% | EPISODEONE | 10 | The main characters are usually introduced in it |
| 39% | ISABELSANFORD | 13 | Actress who played Louise Jefferson, the main character on the '70s sitcom "The Jeffersons" which is one of the longest-running sitcoms: 2 wds. |
| 38% | SEINFELD | 8 | Sitcom whose four main characters are convicted of a crime in the final episode |
| 38% | NEWYORK | 7 | City in which the sitcom Seinfeld is set |
| 38% | ELF | 3 | Holiday movie in which Will Ferrell's character journeys from the North Pole |
| 38% | OURTOWN | 7 | Play in which the Stage Manager is a character |
| 38% | APE | 3 | What the main character in "Mighty Joe Young" was |
| 37% | FLEABAG | 7 | 2019 Emmy-winning show in which the title character is never referred to by her name |
| 36% | RYU | 3 | Main character in Capcom's Street Fighter series whose "special move" was the subject of a scientific work last year |
| 36% | LULU | 4 | Opera in which Jack the Ripper is a character |
| 36% | TORRANCE | 8 | Jack __, main character in S. King's The Shining |
| 36% | PETERGRIFFIN | 12 | The main character and father of the family in the American sitcom, "Family Guy": 2 wds. |
| 36% | TED | 3 | ___ Danson, actor who played the main character Sam Malone in the '80s sitcom "Cheers" |
| 35% | JUNGLE | 6 | Mowgli is the main character in The __ Book |
| 35% | THESIMPSONS | 11 | Fox animated sitcom in which 17-Across voices the recurring character Fat Tony: 2 wds. |
| 35% | PENNYWISE | 9 | Evil clown who is the main character in Stephen King's novel "It" |
| 35% | TABOO | 5 | Party game in which the utterance of certain words are forbidden |
| 35% | OMAN | 4 | Land in which political parties are banned |
| 35% | OMAN | 4 | Country in which political parties are banned |
| 35% | KUOMINTANG | 10 | Political party in China known as the KMT whose first president was Song Jiaoren |
| 34% | RAIDER | 6 | Lara Croft is the main character in Tomb __ |
| 34% | CROMWELL | 8 | Thomas, the main character in Mantel's Wolf Hall |
| 34% | HUNGARY | 7 | Country in which the Rubik's cube was invented |
| 34% | OFFRED | 6 | Main character in The Handmaid's Tale |