| 100% | ARENTI | 6 | Smug question in response to praise |
| 63% | AREYOU | 6 | Question in response to "I am" |
| 62% | AMI | 3 | Question in response to an insult, maybe |
| 60% | WHOWANTSTOKNOW | 14 | Sassy question in response to a question |
| 60% | HOWSOON | 7 | Question in response to "I need this in a hurry" |
| 58% | ANSWERS | 7 | Solutions given in response to questions |
| 56% | NEWPHONEWHODIS | 14 | Snarky text in response to an unwanted question |
| 55% | SOON | 4 | Response to the question in 38-Across |
| 54% | INTHISECONOMY | 13 | Jokey question in response to a statement that may have nothing to do with money |
| 54% | PLEA | 4 | What a defendant enters in response to a judge's question |
| 49% | THISOLDTHING | 12 | Question asked modestly in response to "That looks great on you" |
| 48% | ITRY | 4 | Response to praise, perhaps |
| 47% | WHATSSOFUNNY | 12 | Question asked in response to the starts of both words in 20-, 28- and 48-Across |
| 47% | UCONNERYALE | 11 | Stammering, initially incorrect response to the trivia question "Which Constitution State college is in the Ivy League?"? |
| 46% | ITRY | 4 | Humble response to praise |
| 46% | ITRY | 4 | Modest response to praise |
| 46% | WINCESAT | 8 | Flinches in response to |
| 45% | REACTS | 6 | Acts in response to something |
| 45% | ACTSON | 6 | Takes steps in response to |
| 45% | ACTON | 5 | Do something in response to |
| 45% | ANSWERS | 7 | Responses to questions |
| 45% | ITRY | 4 | Modest response to praise (2 wds.) |
| 45% | REACT | 5 | Show emotion in response to something |
| 45% | PARENTSTRIKE | 12 | Walkout in response to unruly kids? |
| 45% | ILLGETIT | 8 | Words in response to a doorbell |
| 45% | ENCORE | 6 | Extra performance in response to applause |
| 45% | BOW | 3 | Bend over in response to applause |
| 45% | ANSWER | 6 | Response to a question |
| 44% | REFLEX | 6 | Involuntary movement in response to a stimulus |
| 44% | AMEN | 4 | Word shouted in response to a pastor |