| 100% | GOODASHELL | 10 | Song on 46-Across's EP "Coconut Oil" that became a Billboard hit after she performed it at the 2019 MTV Video Music Awards (3 wds.) |
| 31% | TEMPO | 5 | 46-Across song featuring Missy Elliott that was nominated for the 2019 MTV Video Music Award for Best Power Anthem |
| 30% | HOTGIRLSUMMER | 13 | Best Power Anthem winner at the 2019 MTV Video Music Awards |
| 29% | IFALLAPART | 10 | Song by 42-Across that became a hit after a live-performance video went viral in 2017 (3 wds.) |
| 29% | CAMILACABELLO | 13 | "Señorita" singer who shared the 2019 MTV Video Music Award for Best Collaboration with 18-Across (2 wds.) |
| 29% | SHAWNMENDES | 11 | "Señorita" singer who shared the 2019 MTV Video Music Award for Best Collaboration with 32-Across (2 wds.) |
| 29% | PIECEOFME | 9 | Song by 32-Across that won three MTV Video Music Awards in 2008, including Video of the Year (3 wds.) |
| 28% | HIGHESTIN | 9 | With 43-Across, 2019 Travis Scott song that debuted at #1 on the Billboard Hot 100: 2 wds. |
| 28% | OHMYGOD | 7 | 2021 song that became Adele's eighth top 10 hit on the Hot 100: 3 wds. |
| 28% | JUICE | 5 | Song from 46-Across's album "Cuz I Love You" that won the 2019 Soul Train Music Award for Video of the Year |
| 27% | ONEDIRECTION | 12 | Boy band that was the Best New Artist at the 2012 MTV Video Music Awards: 2 wds. |
| 27% | ESPRESSO | 8 | Sabrina Carpenter hit song that peaked at No. 3 on the Billboard Hot 100 in 2024 |
| 27% | MARIAHCAREY | 11 | Her 2009 hit "Obsessed" reentered the Billboard charts in 2019 thanks to a viral dance challenge video: 2 wds. |
| 27% | TAYLORSWIFT | 11 | "Lover" singer who won three 2019 MTV Video Music Awards, including Video of the Year (2 wds.) |
| 27% | THELONDON | 9 | Young Thug song featuring J. Cole and Travis Scott that was nominated for the 2019 MTV Video Music Award for Song of Summer (2 wds.) |
| 26% | TOPNEWARTIST | 12 | Billboard Music Award for a performer at the beginning of their career: 3 wds. |
| 26% | BIGOLEFREAK | 11 | 2019 Megan Thee Stallion hit that was her first song to make the Billboard charts (3 wds.) |
| 26% | BLACKPINK | 9 | "How You Like That" band who won Song of Summer at the 2020 MTV Video Music Awards |
| 25% | BILLIEEILISH | 12 | "Bad Guy," 17-Across, and 42-Across singer who won Best New Artist at the 2019 MTV Video Music Awards (2 wds.) |
| 25% | SINGLELADIES | 12 | "___ (Put a Ring on It)," a song by Beyonce that has become one of the best-selling singles of all time: 2 wds. |
| 25% | RODSTEWART | 10 | Singer who performed his song "Infatuation" to open the first MTV Video Music Awards, in 1984: 2 wds. |
| 25% | JONASBROTHERS | 13 | 2008 American Music Awards New Artist of the Year whose fifth studio album, "Happiness Begins," debuted at #1 on the U.S. "Billboard" 200 in 2019 (2 wds.) |
| 25% | MILEYCYRUS | 10 | "Don't Call Me Angel" co-singer whose 2019 EP "She Is Coming" debuted at #5 on the U.S. Billboard 200 (2 wds.) |
| 25% | SLEDGEHAMMER | 12 | Song that accounted for 9 of the 10 MTV Video Music Awards won by 17-Across in 1987 |
| 25% | SICKOMODE | 9 | Travis Scott song that won the 2019 Billboard Music Award for Top Streaming Song (Audio) (2 wds.) |
| 25% | PETERGABRIEL | 12 | "Big Time" singer who won 10 MTV Video Music Awards in 1987, the most wins ever in a single night: 2 wds. |
| 25% | UPSIDEDOWN | 10 | 1980 50-Across song that hit #1 on the Billboard Hot 100, Disco, and Soul charts (2 wds.) |
| 25% | FAMILYAFFAIR | 12 | 28-Across song that spent six weeks at #1 on the Billboard Hot 100 in 2001 (2 wds.) |
| 24% | ALLIWANTFOR | 11 | With 33-Across, holiday tune that hit #1 on the Billboard charts in 2019, 2020, and 2021: 4 wds. |
| 24% | TAYLORSWIFT | 11 | "Shake It Off" singer who's had seven songs debut at #1 on the Billboard Hot 100: 2 wds. |