| 100% | SAVANNAH | 8 | Southern city that's the setting for "Midnight in the Garden of Good and Evil" |
| 87% | SAVANNAH | 8 | Georgia city that's the setting of Midnight in the Garden of Good and Evil |
| 49% | EVIL | 4 | "Midnight in the Garden of Good and ___" |
| 44% | EDEN | 4 | Garden that contained the tree of the knowledge of good and evil |
| 41% | ARLEN | 5 | Fictional town in Texas that is the setting for "King of the Hill" |
| 41% | ARLES | 5 | City that's the setting for several van Gogh paintings |
| 40% | QUAHOG | 6 | Fictional Rhode Island city that's the setting for 15-Across |
| 39% | TROY | 4 | You can visit this city in Turkey that serves as the setting for Homer's "Iliad" (3/4) |
| 39% | COMICBOOK | 9 | Setting for each of the places in 15-, 21-, and 41-Across: 2 wds. |
| 38% | TARSUS | 6 | City in southern Turkey and the birthplace of Saint Paul |
| 38% | SERPENT | 7 | Speaker of the words "Ye shall be as gods, knowing good and evil," in Genesis |
| 38% | TOLLS | 5 | "For Whom the Bell ___," novel by Ernest Hemingway, set in the Spanish Civil War and is regarded as one of his best works |
| 38% | YEAR | 4 | "A Good ___," 2006 rom-com that is set in the vineyards of France |
| 38% | COSMO | 5 | Carrie Bradshaw's choice of cocktail in "Sex and the City," for short |
| 38% | LYNYRDSKYNYRD | 13 | American rock band formed in 1964 that still performs live and is best known for popularizing the Southern rock genre: 2 wds. |
| 38% | IOWA | 4 | State that's the setting for "The Bridges of Madison County" |
| 38% | CASTLE | 6 | The ___ of Otranto, a looming fortress that sets the stage for supernatural events in Horace Walpole's eponymous Gothic tale |
| 38% | THRILLER | 8 | Album by Michael Jackson and Quincy Jones that won the Grammy for Album of the Year in 1984 |
| 38% | SEINE | 5 | River that's the setting for van Gogh's "Fishing in Spring" |
| 38% | EVE | 3 | Cain and Abel's mother, in the Garden of Eden |
| 37% | ORIENTEXPRESS | 13 | Train that's the setting for murder in a 2017 remake directed by Kenneth Branagh (2 wds.) |
| 37% | PADUA | 5 | University city in Veneto, N E Italy; setting for much of William Shakespeare's play The Taming of the Shrew |
| 37% | EDEN | 4 | Biblical garden with the Tree of the Knowledge of Good and Evil |
| 37% | NOLA | 4 | City that's the subject of the book Musical Gumbo, for short |
| 37% | ARGOS | 5 | Greek city that's one of the oldest in Europe |
| 37% | EDEN | 4 | Biblical garden home to the tree of the knowledge of good and evil |
| 36% | GIMME | 5 | Word repeated thrice in the title of a 1979 ABBA song that asks for "A Man After Midnight" |
| 36% | BYATT | 5 | A S —, author of the novels Still Life and The Virgin in the Garden |
| 36% | PETRA | 5 | Abandoned city in Jordan that was "lost" and hidden in the desert for years |
| 36% | AUSTINBUTLER | 12 | Best Actor Oscar nominee for his portrayal of the "King of Rock and Roll" in the 2022 film "Elvis" (2 wds.) |