| 100% | TEDDYBEAR | 9 | Stuffed animal that Seth MacFarlane provided the voice for in a hit 2012 movie: 2 wds. |
| 36% | FAMILYGUY | 9 | Seth MacFarlane animated series featuring the voices of 15-Across, 26-Across, and 34-Across that debuted in 1999 (2 wds.) |
| 34% | BEANIEBABIES | 12 | Small stuffed animals that were very popular in the 1990s (2 wds.) |
| 34% | TED | 3 | Seth MacFarlane movie about a stuffed animal that comes to life |
| 33% | FIREWORK | 8 | Hit song by Katy Perry that was nominated for a Grammy for Record of the Year in 2012 |
| 33% | DRNO | 4 | Villain with the title role in a 1962 movie that introduced 007: 2 wds. |
| 33% | TEDDYBEAR | 9 | Stuffed animal that's more cuddly than a grizzly: 2 wds. |
| 32% | TED | 3 | 2012 animated movie in which Seth MacFarlane has voiced a toy bear |
| 32% | TED | 3 | Seth MacFarlane movie about a talking stuffed animal |
| 32% | TOYSTORY | 8 | 1995 movie where Tom Hanks provided the voice of a doll named Woody: 2 wds. |
| 32% | AMERICANDAD | 11 | Animated show in which the father (voiced by Seth MacFarlane) works for the CIA: 2 wds. |
| 31% | TED | 3 | A 2012 comedy film in which Seth MacFarlane voices the titular trash-talking teddy bear |
| 31% | CAREBEARS | 9 | Line of colorful stuffed animals introduced in the 1980s: 2 wds. |
| 30% | JULIANASSANGE | 13 | WikiLeaks whistleblower portrayed by Benedict Cumberbatch in a movie that opens nationally next week: 2 wds. |
| 29% | DONTYOUWANTME | 13 | The Human League song that was a No. 1 hit in 1982 (4 wds.) |
| 29% | ARIANAGRANDE | 12 | "7 Rings" singer who reimagined 18-Across in a 2024 hit with the same title: 2 wds. |
| 29% | NIGHTWATCH | 10 | Jayne Anne Phillips novel set in a post-Civil War asylum that's on the longlist for the 2023 National Book Award for Fiction (2 wds.) |
| 29% | ITSSOEASY | 9 | Crickets song that was a #5 hit for 32-Across in 1977: 3 wds. |
| 28% | COTTONEYEDJOE | 13 | Traditional American folk song that was the inspiration for a 1994 hit by Swedish band Rednex: 2 wds., hyph. |
| 28% | LEEGREENWOOD | 12 | "I.O.U." singer who had a hit in 2001 with "God Bless the U.S.A.": 2 wds. |
| 28% | AINTITFUN | 9 | Hit single by Paramore that won a Grammy Award for Best Rock Song in 2015 (3 wds.) |
| 28% | ORIENTEXPRESS | 13 | Train that's the setting for murder in a 2017 remake directed by Kenneth Branagh (2 wds.) |
| 28% | YOUREALLYGOTME | 14 | 1964 hit for the Kinks that's in the Grammy Hall of Fame: 4 wds. |
| 28% | ABOUTDAMNTIME | 13 | 2022 Lizzo hit single that won a Grammy for Record of the Year (3 wds.) |
| 28% | THEROUNDHOUSE | 13 | Louise Erdrich novel that won the National Book Award for Fiction in 2012 (3 wds.) |
| 28% | MYRTLEWILSON | 12 | She is killed in a hit-and-run accident in "The Great Gatsby": 2 wds. |
| 28% | GINARODRIGUEZ | 13 | Actress who voices Mary in the movie "The Star": 2 wds. |
| 28% | YMCA | 4 | Song that was a hit for a spell in the 1970s? |
| 28% | MARYTRAVERS | 11 | Folk singer who, in a trio with Peter and Paul, sang the 1963 hit "Puff, the Magic Dragon": 2 wds. |
| 28% | BEAT | 4 | "___ It," a hit single from Michael Jackson's album in 16a that won a Grammy for "Record of the Year" |