| 100% | TAXES | 5 | Subject of a major bill before the U.S. Senate |
| 43% | OPIOID | 6 | Subject of a U.S. drug epidemic |
| 42% | UFOS | 4 | Subjects of a U.S. Air Force cover-up? |
| 42% | CLINTON | 7 | The surname of a former US president, Bill __ |
| 42% | AMER | 4 | From the U.S. of A. |
| 42% | DES | 3 | ___ Moines, Iowa's capital that is a major center of the US insurance industry |
| 41% | PLUTO | 5 | Subject of a major downgrade in 2006 |
| 40% | RECT | 4 | Shape of a U.S. dollar bill |
| 40% | CSPAN | 5 | TV channel that streams the U.S. Senate and House of Representatives |
| 40% | RUBIO | 5 | Marco of the U.S. Senate |
| 40% | HARRIS | 6 | Kamala of the U.S. Senate |
| 39% | IRAN | 4 | With whom the U.S. pulled out of a nuclear deal |
| 39% | DDT | 3 | Target of a 1972 ban in the U.S. |
| 39% | WOMEN | 5 | 22% of the U.S. Senate |
| 39% | ATTN | 4 | Abbreviation before the name of a business letter's recipient |
| 39% | BREXIT | 6 | Subject of a June 2016 U.K. referendum |
| 39% | OLDMACDONALD | 12 | Subject of a children's song associated with the vowels in the answer to each starred clue |
| 38% | BRUNEIANS | 9 | Subjects of a sultanate on the coast of Borneo |
| 38% | ETHICS | 6 | Subject of a Senate committee with an interest in gifts |
| 38% | ARBOR | 5 | Subject of a celebration on the last Friday in April |
| 38% | REDSEA | 6 | Site of a major part of the Bible? |
| 37% | UFOS | 4 | In 2021, the U.S. Department of Defense established a group to examine them (abbr.) |
| 37% | TWOS | 4 | U.S. bills that depict the Declaration of Independence signing on their backs |
| 37% | OBAMA | 5 | Subject of a Kehinde Wiley portrait in the National Portrait Gallery |
| 37% | PREDICATE | 9 | Part of a sentence, tells what the subject's doing |
| 37% | STAR | 4 | Representation of a state on the U.S. flag |
| 37% | LUTE | 4 | Subject of a lesson for Katharina in "The Taming of the Shrew" |
| 37% | LUTE | 4 | Subject of a lesson for Katherine in “The Taming of the Shrew” |
| 37% | LBJ | 3 | Subject of the Pulitzer-winning bio "Master of the Senate" |
| 37% | VETO | 4 | Governor's rejection of a bill the legislature has passed |