| 100% | DRUG | 4 | Substance with a physiological effect |
| 56% | ACID | 4 | Substance with a low pH |
| 55% | ACID | 4 | Substance with a pH under 7 |
| 54% | ALKALI | 6 | Substance with a pH higher than 7 |
| 54% | ALKALIS | 7 | Substances with a pH more than 7 |
| 52% | MENTHOL | 7 | Cooling substance with a strong minty scent |
| 52% | STOMP | 5 | Dance with a percussive effect |
| 52% | DAMPER | 6 | Something with a depressing effect |
| 50% | SMEAR | 5 | Smudge with a greasy substance |
| 49% | EMOLLIENT | 9 | Cream with a skin softening effect |
| 48% | WAXED | 5 | Removed body hair with a hot substance |
| 48% | DAUB | 4 | To liberally coat with a thick substance |
| 46% | CARWAX | 6 | Substance applied with a chamois |
| 46% | PAVE | 4 | Coat the road or an area with a hard substance |
| 45% | DOPPLER | 7 | Physicist Christian with a namesake effect |
| 45% | TOXIC | 5 | Like a substance with a skull-and-crossbones label |
| 45% | ANTIVENOM | 9 | Substance that can reverse a snake bite's effects |
| 44% | CHALKS | 6 | Prepares a pool cue with powdery substance |
| 44% | PEARL | 5 | Substance associated with a thirtieth wedding anniversary |
| 44% | PEARL | 5 | Substance associated with a 30th wedding anniversary |
| 44% | ADVERSELY | 9 | In a harmful way, with damaging effects |
| 44% | PLACEBO | 7 | A harmless pill with no effect to trick the brain |
| 43% | ACIDIC | 6 | Substance quality with a PH lower than 7 |
| 43% | SOLUTION | 8 | Answer; mixture of a liquid with other substances |
| 41% | OLAY | 4 | Skin care brand with a Fresh Effects line |
| 41% | OLAY | 4 | Skin care brand with a Total Effects line |
| 39% | OLAY | 4 | Skin-care brand with a Total Effects product line |
| 38% | AWRY | 4 | With a twist? |
| 38% | NODTO | 5 | With a ___ (recognizing) |
| 38% | GLADLY | 6 | With a smile |