| 100% | SMALLVILLE | 10 | Superhero TV series set at Clark Kent and Lana Lang's high school |
| 40% | GLEE | 4 | TV series mostly set at William McKinley High School |
| 38% | GLEE | 4 | Musical TV series starring Lea Michele that is set at William McKinley High School |
| 37% | WHY | 3 | "13 Reasons ___," teen drama TV series starring Dylan Minnette that is set at Liberty High School |
| 37% | BLOCK | 5 | "On My ___," teen drama TV series starring Sierra Capri that is set at Freeridge High School |
| 37% | NEVER | 5 | "___ Have I Ever," comedy TV series starring Maitreyi Ramakrishnan that is set at Sherman Oaks High School |
| 36% | LANG | 4 | Lana —, high school girlfriend of Clark Kent in the Superman comic book series |
| 35% | GLEE | 4 | Fox series set at William McKinley High School |
| 34% | GLEE | 4 | TV show set at William McKinley High School |
| 34% | DERRYGIRLS | 10 | British TV series set at Our Lady Immaculate secondary school in Northern Ireland (2 wds.) |
| 33% | GLEE | 4 | TV series that took place at McKinley High School in Ohio |
| 33% | LANALANG | 8 | High school girlfriend of Clark Kent in the Superman comic book series |
| 32% | FTROOP | 6 | 1960's TV series set at Fort Courage |
| 32% | SEVERANCE | 9 | TV series set at Lumon Industries |
| 31% | NEWHART | 7 | TV series set at the Stratford Inn |
| 31% | GLEE | 4 | TV musical comedy set at William McKinley High School |
| 30% | SUITS | 5 | TV series set at the Pearson Specter Litt law firm |
| 30% | UPSTAIRSDOWNSTAIRS | 18 | 1970s TV series set at 165 Eaton Place |
| 29% | GLEE | 4 | Musical series set at McKinley High |
| 29% | CSI | 3 | TV series that spawned an exhibit at Chicago's Museum of Science and Industry |
| 28% | SEVERANCE | 9 | Apple TV+ series set at Lumon Industries |
| 28% | GLEE | 4 | TV series about a high school choir group |
| 28% | GLEE | 4 | TV series about a high school show choir |
| 28% | GREASE | 6 | Musical set at Rydell High School |
| 28% | APBIO | 5 | Sitcom set at Whitlock High School |
| 27% | HIGH | 4 | ___ school, setting for many TV series like "Riverdale" and "Wednesday" |
| 27% | BOTTLEEPISODE | 13 | TV series installment with a limited set and cast |
| 27% | EMILYMEADE | 10 | Actress who plays Aimee, Jill's high school friend on the hit TV series "The Leftovers": 2 wds. |
| 27% | GLEE | 4 | Former TV series about high school singers |
| 27% | TAXI | 4 | Classic TV series set in a garage with Elaine, Latka, and Louie |