| 100% | UNTILDAWN | 9 | Survival horror adventure video game in which Rami Malek (birthday today) appears as Josh Washington: 2 wds. |
| 35% | GARYCOLEMAN | 11 | "Diff'rent Strokes" star who appears as himself in the 2003 video game "Postal 2": wds. |
| 34% | FIXITFELIXJR | 12 | Video game in which 20-Across's title character appears: 3 wds. |
| 33% | SNOOPDOGG | 9 | "Gin and Juice" rapper who appears as himself in the 2003 video game "True Crime: Streets of LA": 2 wds. |
| 33% | PHILCOLLINS | 11 | Former Genesis drummer who appears as himself in the 2006 video game "Grand Theft Auto: Vice City Stories": 2 wds. |
| 33% | DREWCAREY | 9 | "The Price Is Right" host who appears as himself in the 2001 video game "The Sims: House Party": 2 wds. |
| 30% | THEMUSEUM | 9 | "Night at ___," fantasy-comedy film in which Rami Malek plays the mummy of Pharaoh Ahkmenrah: 2 wds. |
| 28% | FREEZETAG | 9 | Game in which players stand still when touched: 2 wds. |
| 28% | THEMATRIX | 9 | A 1999 Sci-Fi film in which Keanu Reeves - whose birthday it is today - portrays the main character, named "Neo": 2 wds. |
| 28% | SUGARRUSH | 9 | Kart-racing video game in 20-Across: 2 wds. |
| 27% | PIXELS | 6 | 2015 fantasy movie about video games in which Josh Gad plays a gaming expert |
| 27% | HEROSDUTY | 9 | First-person shooter video game in 20-Across: 2 wds. |
| 27% | RESIDENTEVIL | 12 | Survival-horror video game series, or a 2002 Milla Jovovich film: 2 wds. |
| 27% | ANIMALCROSSING | 14 | Video game series in which Bells are used as currency |
| 26% | STICKERSTAR | 11 | "Paper Mario: ___" (2012 Nintendo game in which Mario peels off collectibles): 2 wds. |
| 26% | WIIU | 4 | Nintendo video game console released in 2012: 2 wds. |
| 26% | LIFESUPPORT | 11 | A 2007 movie in which Queen Latifah's (birthday today) character was based on Ana Wallace: 2 wds. |
| 26% | COLORSPLASH | 11 | "Paper Mario: ___" (2016 Nintendo game in which Mario uses a Paint Hammer): 2 wds. |
| 26% | SPAWN | 5 | Appear, as in a video game |
| 25% | THEHURRICANE | 12 | 1999 film in which Denzel Washington played an imprisoned boxer: 2 wds. |
| 25% | ANTWONEFISHER | 13 | 2002 film in which Denzel Washington played a Navy psychiatrist: 2 wds. |
| 25% | FOURTHESTATE | 12 | "The ___," a novel by Jeffrey Archer in which a character was based on media mogul Rupert Murdoch (birthday today): 2 wds. |
| 25% | TOMBRAIDER | 10 | 2018 action film in which Alicia Vikander (birthday today) played the role of Lara Croft: 2 wds. |
| 25% | FREDDIEMERCURY | 14 | Real-life musician portrayed by Rami Malek in 2018's "Bohemian Rhapsody": 2 wds. |
| 25% | RAYDONOVAN | 10 | A crime drama in which Liev Schreiber stars as the titular character: 2 wds. |
| 25% | THEMATRIX | 9 | Movie in which Keanu Reeves, as Neo, says "I know kung fu": 2 wds. |
| 25% | HALO | 4 | Video game in which players battle the Covenant |
| 25% | SIMCITY | 7 | Video game in which you build a metropolis |
| 25% | INSIDEMAN | 9 | 2006 film in which Denzel Washington plays a detective negotiating for the release of hostages: 2 wds. |
| 24% | TOMBRAIDER | 10 | Adventure video game adapted into films starring Angelina Jolie and Alicia Vikander: 2 wds. |