| 100% | SELMALAGERLOF | 13 | Swedish novelist and short story writer who was the first woman honored with the Nobel Prize in Literature (2 wds.) |
| 88% | SINCLAIRLEWIS | 13 | Minnesota novelist and short story writer who was the first American honored with the Nobel Prize in Literature (2 wds.) |
| 69% | WOLESOYINKA | 11 | Nigerian playwright and novelist who was the first African honored with the Nobel Prize in Literature (2 wds.) |
| 55% | EDITHWHARTON | 12 | 13-Across and 25-Across writer who was the first woman to win a Pulitzer Prize in Literature, for her 1920 novel "The Age of Innocence" (2 wds.) |
| 48% | KAZUOISHIGURO | 13 | British novelist who wrote 19-Across and 31-Across and was awarded the 2017 Nobel Prize in Literature (2 wds.) |
| 47% | ALICE | 5 | With 7-Across, short story writer who won the 2013 Nobel Prize in Literature |
| 46% | JENNIFERLOPEZ | 13 | 15-Across and 27-Across singer who was the first woman honored with a "Billboard" Icon Award (2 wds) |
| 45% | ALICEMUNRO | 10 | Canadian short story author who won the 2013 Nobel Prize in Literature: 2 wds. |
| 45% | TONIMORRISON | 12 | "Beloved" author who died August 5, and who was the first African-American woman to win a Nobel Prize: 2 wds. |
| 44% | TONIMORRISON | 12 | "Beloved" novelist who was awarded the Nobel Prize in Literature in the year 1993: 2 wds. |
| 43% | MUHAMMADYUNUS | 13 | Social entrepreneur and economist who was the first Bangladeshi to win the Nobel Peace Prize: 2 wds. |
| 42% | CURIE | 5 | Last name of the first woman to win the Nobel Prize and who is credited with the theory of radioactivity |
| 39% | TENZINGYATSO | 12 | 14th Dalai Lama who was the first Tibetan to win the Nobel Peace Prize: 2 wds. |
| 39% | PEARLSBUCK | 10 | First American woman to win the Nobel Prize in Literature, in 1938: 3 wds. |
| 39% | JANEADDAMS | 10 | First American woman to be awarded the Nobel Peace Prize, in 1931: 2 wds. |
| 39% | MOTHERTERESA | 12 | Albanian-Indian nun who was the first Asian woman (She adopted Indian citizenship) to win the Nobel Peace Prize: 2 wds. |
| 39% | KATEWILHELM | 11 | "The Mile-Long Spaceship" short-story writer who was inducted into the Science Fiction and Fantasy Hall of Fame in 2003 (2 wds.) |
| 39% | RAYBRADBURY | 11 | "S Is for Space" short-story writer who was inducted into the Science Fiction and Fantasy Hall of Fame in 1999 (2 wds.) |
| 39% | MARGARETCOURT | 13 | Australian tennis player who was the first woman to win the Grand Slam in the Open Era: 2 wds. |
| 38% | BOBDYLAN | 8 | "Blowin' in the Wind" singer-songwriter who was awarded the Nobel Prize in Literature in the year 2016: 2 wds. |
| 38% | FRANCESARNOLD | 13 | First American woman to win the Nobel Prize in Chemistry, in 2018: 2 wds. |
| 38% | ALICEMUNRO | 10 | Canadian writer who won the 2013 Nobel Prize in Literature (2 wds.) |
| 38% | LOUISEGLUCK | 11 | American writer who won the 2020 Nobel Prize in Literature (2 wds.) |
| 38% | OLGATOKARCZUK | 13 | Polish writer who won the 2018 Nobel Prize in Literature (2 wds.) |
| 38% | SOLANGEKNOWLES | 14 | 12-Across and 28-Across singer who was the first recipient of the "Billboard" Women in Music Impact Award (2 wds.) |
| 38% | SAULBELLOW | 10 | "Herzog" author and Nobel Prize winner who was honored with a 2024 US postage stamp: 2 wds. |
| 38% | HERTAMULLER | 11 | Romanian-German writer who won the 2009 Nobel Prize in Literature (2 wds.) |
| 38% | TONIMORRISON | 12 | First African-American woman to win the Nobel Prize for Literature (2 wds.) |
| 38% | MARIARESSA | 10 | Filipino American journalist and Nobel Peace Prize winner who was honored with a 2024 Carnegie Great Immigrants award: 2 wds. |
| 38% | GORDIMER | 8 | "My Son's Story" writer, Nadine ___ who was awarded the Nobel Prize in Literature in the year 1991 |