| 100% | BUBBLES | 7 | Sweet, blue '90s superhero from the animated series "The Powerpuff Girls" who fashions 2 pigtails with beaded bands |
| 51% | PICKLES | 7 | Angelica ___, bossy toddler from the '90s animated series "Rugrats" who fashions 2 pigtails tied with bows |
| 43% | ELIZA | 5 | ___ Thornberry, protagonist from the late '90s animated series "The Wild Thornberrys" who fashions 2 pigtails |
| 37% | DEE | 3 | When repeated, Dexter's sister from the '90s animated show "Dexter's Laboratory" who fashions 2 pigtails |
| 32% | DOG | 3 | Jake the ___, Finn's best friend from the animated series "Adventure Time," who is associated with the color at 42a |
| 32% | KIPOANDTHEAGE | 13 | With 32-Across, animated series about a girl from beneath the Earth's surface: 4 wds. |
| 28% | BUBBLES | 7 | The blonde Powerpuff girl who wears a blue outfit |
| 27% | FROZONE | 7 | Superhero from "The Incredibles" who has the ability to freeze things with his fingertips |
| 27% | DAY | 3 | Jessica ___, bubbly teacher from the TV series "New Girl" who randomly breaks into songs |
| 26% | LISASIMPSON | 11 | Animated girl who was in the finals of a crossword puzzle tournament: 2 wds. |
| 25% | ROGERMOORE | 10 | Actor from the TV series "The Saint", who has played the role of James Bond in seven movies : 2 wds. |
| 25% | KRISTENWIIG | 11 | "Bridesmaids" actress who voices Brenda, a hot dog bun, in the animated series "Sausage Party: Foodtopia": 2 wds. |
| 25% | BOO | 3 | Toddler from the 2001 Disney movie "Monsters Inc.," who wears a fringe along 2 tiny pigtails |
| 25% | STEVENYEUN | 10 | "Beef" actor who voices Mark Grayson in the Amazon animated series "Invincible": 2 wds. |
| 25% | PEG | 3 | ___ Bundy, character from the series "Married... with Children" who qualifies to be a couch potato |
| 25% | BRANFORD | 8 | With 53-Across, saxophonist who led the Tonight Show Band from 1992-1995 |
| 25% | MOON | 4 | Sailor ___, '90s anime princess character who fashions 2 long twin pigtails |
| 24% | PAULREISER | 10 | "Mad About You" actor who voices Elliot Cooper on the Netflix animated series "Long Story Short": 2 wds. |
| 24% | TRANSFORMERS | 12 | "The ___," popular animated robot superhero series from the 1980s which was based on Hasbro's toy line |
| 24% | TOMHIDDLESTON | 13 | Actor who plays Loki in the Disney+ Marvel alternate-universe animated series "What If ...?": 2 wds. |
| 24% | POWERS | 6 | Stefanie —, actress who starred as April Dancer in 1960s US television series The Girl from UNCLE |
| 24% | STIEGLARSSON | 12 | Swedish author whose Millennium trilogy ended with "The Girl Who Kicked the Hornets' Nest": 2 wds. |
| 24% | BOBTHORNTON | 11 | Billy ___, "Bad Santa" actor who is the vocalist of the blues rock band The Boxmasters: 2 wds. |
| 24% | TEENAGEMUTANT | 13 | "___ Ninja Turtles," popular animated series from the 1980s about characters named after Italian Renaissance artists: 2 wds. |
| 24% | DEEDEE | 6 | Dexter's older sister who loves ballet in the animated TV series, "Dexter's Laboratory": 2 wds. |
| 24% | ROONEYMARA | 10 | "Carol" actress who starred in 2011's "The Girl With the Dragon Tattoo": 2 wds. |
| 24% | MAYARUDOLPH | 11 | "Up All Night" actress who performed with the band The Rentals: 2 wds. |
| 24% | PROUDMARY | 9 | Girl in a Tina Turner song from the soundtrack of "What's Love Got to Do with It": 2 wds. |