| 100% | DAVIDLETTERMAN | 14 | Talk-show host who retired in 2015 and unretired in 2018: 2 wds. |
| 65% | PHILCOLLINS | 11 | "Against All Odds" singer who retired in 2011 and unretired in 2015: 2 wds. |
| 58% | CAMERONDIAZ | 11 | "The Mask" actress who retired in 2014 and unretired in 2022: 2 wds. |
| 54% | MARIEOSMOND | 11 | Singer and talk show host who has been a spokesperson for Nutrisystem: 2 wds. |
| 54% | GEORGELOPEZ | 11 | Talk show host who plays a teacher in "Spare Parts": 2 wds. |
| 54% | JIMMYKIMMEL | 11 | Late-night talk show host who voiced the father in "The Boss Baby": 2 wds. |
| 52% | JIMMYKIMMEL | 11 | Talk show host who recently hosted the Oscars for the second year in a row: 2 wds. |
| 52% | OPRAHWINFREY | 12 | TV talk show host who received the NAACP's Spingarn Medal in 2000: 2 wds. |
| 52% | ELLENDEGENERES | 14 | Comedian and daytime talk host who appeared in the "Girls Like You" video: 2 wds. |
| 50% | RICKILAKE | 9 | Former talk show host who premiered her documentary "Weed the People" at the SXSW festival in Austin: 2 wds. |
| 50% | ROSIEODONNELL | 13 | Host of a self-titled talk show who hosted the 1999 and 2000 Grammy ceremonies: 2 wds. |
| 50% | JOHNMULANEY | 11 | Stand-up comic and former "SNL" writer who first returned to host in 2018: 2 wds. |
| 50% | CAROLBURNETT | 12 | Comedian and variety show host who was awarded the Mark Twain Prize in 2013: 2 wds. |
| 49% | JOHNNYCARSON | 12 | American talk show host and comedian who hosted "The Tonight Show" for three straight decades: 2 wds. |
| 49% | DONALDGLOVER | 12 | Rapper and "Atlanta" star who both hosted "SNL" and performed as the musical guest in 2018: 2 wds. |
| 48% | TAVISSMILEY | 11 | PBS talk show host who formerly had a show on NPR: 2 wds. |
| 48% | LEEZA | 5 | Talk show host who won "The Celebrity Apprentice" in 2015, familiarly |
| 47% | JOHNCENA | 8 | Professional wrestler and actor who hosted the Nickelodeon Kids' Choice Awards in 2017 and 2018: 2 wds. |
| 47% | ROSIEODONNELL | 13 | American TV presenter and activist who has hosted several daytime television talk shows and was a moderator on "The View": 2 wds. |
| 47% | EMMATHOMPSON | 12 | "Love Actually" actress who plays veteran late-night talk show host Katherine Newbury in "Late Night" (2 wds.) |
| 47% | DOROTHYHAMILL | 13 | Retired American figure skater and Olympian who participated in season 16 of the TV show "Dancing with the Stars": 2 wds. |
| 47% | CHARLESBARKLEY | 14 | Basketball Hall of Famer nicknamed "the Round Mound of Rebound" who hosted "SNL" in 1993, 2010, 2012, and 2018: 2 wds. |
| 47% | ELLENDEGENERES | 14 | Daytime talk show host who is a vegan: 2 wds. |
| 47% | BENSTILLER | 10 | Host of a 1990s sketch comedy show who starred in and wrote both "Zoolander" movies (2 wds.) |
| 46% | JONSTEWART | 10 | Comedian who was the host of "The Daily Show" till 2015, and has hosted 2 Grammy Award ceremonies: 2 wds. |
| 46% | BLAKESHELTON | 12 | Country singer and "The Voice" judge who both hosted "SNL" and performed as the musical guest in 2015: 2 wds. |
| 46% | JONSTEWART | 10 | "The Daily Show" host who hosted the 2001 and 2002 Grammy ceremonies: 2 wds. |
| 46% | ROSIEODONNELL | 13 | Talk show host who played one of Murphy Brown's many secretaries: 2 wds. |
| 45% | GORDONRAMSAY | 12 | British chef known for his temper, who appears as host or judge in shows like "MasterChef" and "Hell's Kitchen": 2 wds. |
| 45% | JAMESCORDEN | 11 | "The Late Late Show" host who voices Peter Rabbit in 2018's "Peter Rabbit" (2 wds.) |