| 100% | YAPAT | 5 | Talk to persistently and with a big mouth |
| 47% | EWER | 4 | One with a big mouth |
| 47% | CLOWN | 5 | Performer with a big mouth? |
| 47% | IMUS | 4 | Don with a big mouth |
| 47% | EWER | 4 | Pitcher with a big mouth |
| 47% | HIPPO | 5 | Land mammal with a big mouth |
| 46% | NILE | 4 | One with a big mouth in Africa? |
| 43% | EXCAVATOR | 9 | Construction equipment with a big bucket to dig |
| 42% | BOTTLE | 6 | Container for liquids, with a neck and mouth |
| 40% | POGOSTICK | 9 | Toy with a handlebar and a big spring |
| 40% | DORA | 4 | Explorer with a backpack and a talking map |
| 40% | SEW | 3 | To stitch something with a needle and thread |
| 40% | OWL | 3 | Nocturnal bird with a flat face and big eyes |
| 40% | OWL | 3 | Nocturnal bird with a broad head and big eyes |
| 40% | PREDATOR | 8 | Animal with a natural instinct to hunt and kill |
| 40% | SEMI | 4 | Prefix with a meaning akin to "hemi-" and "demi-" |
| 39% | NONO | 4 | Eating pizza with a fork and knife, to New Yorkers |
| 39% | OPRAH | 5 | Talk show mogul with a big book club |
| 39% | DELTA | 5 | Where to find a big mouth |
| 39% | FOURHCLUBS | 10 | Youth groups ... with a hint to 17-, 28- and 44-Across |
| 39% | WHIP | 4 | Beat food with a whisk to incorporate air and produce volume |
| 39% | EWER | 4 | One with a neck, mouth and lip, but no eyes |
| 39% | WAINSCOT | 8 | To line a room with wooden boards and panels |
| 38% | ARTCENTER | 9 | Place with a gallery, and a hint to this puzzle's theme |
| 38% | TWOPARTER | 9 | Story with a cliffhanger, perhaps, and a hint to the starred answers |
| 38% | WHATSTHEMATTER | 14 | Question of concern, with a hint to 20-, 25- and 43-Across |
| 38% | FINDINGNEMO | 11 | 2003 animated film … with a hint to 17-, 32- and 41-Across |
| 38% | ONOFFSWITCH | 11 | Electrical device with a hint to answering 17-, 27- and 48-Across |
| 38% | THEBIGFIVEOH | 12 | Milestone birthday, informally ... with a hint to 20-, 31- and 41-Across |
| 38% | AHAMOMENT | 9 | Sudden insight ... with a hint to 17-, 24-, 40- and 50-Across |