| 100% | AVERY | 5 | Tex —, film cartoon director who created the character Daffy Duck |
| 55% | AVERY | 5 | Tex —, director of cartoon features who created Daffy Duck |
| 47% | AVERY | 5 | Tex —, animator and film director who created canine character Droopy |
| 46% | WES | 3 | ___ Craven, director who created the "Nightmare on Elm Street" film franchise |
| 45% | FRELENG | 7 | Friz —, animated cartoon director who created characters Yosemite Sam and Speedy Gonzalez |
| 45% | JONES | 5 | Chuck —, animated cartoon director who created characters Wile E Coyote and Marvin Martian |
| 44% | MELBLANC | 8 | US actor who voiced the cartoon characters Daffy Duck and Porky Pig |
| 41% | TYLER | 5 | Actor/director Perry who created the character Madea |
| 39% | BILLDANA | 8 | Comedian who created the character Jose Jimenez |
| 39% | VLADIMIRNABOKOV | 15 | Writer who created the character Vivian Darkbloom |
| 39% | TYLER | 5 | Actor Perry who created the character Madea |
| 39% | MORRELL | 7 | David, author who created the character Rambo |
| 39% | TYLER | 5 | Actor and director Perry, who created the Madea character |
| 39% | LOW | 3 | David —, cartoonist who created the character Colonel Blimp |
| 39% | LEE | 3 | Harper ___ who created the character of Atticus Finch |
| 38% | SPEIGHT | 7 | Johnny —, comedy writer who created the character Alf Garnett |
| 38% | STAN | 4 | Lee who created the character referenced in 1-Across |
| 38% | MARCEAU | 7 | Marcel —, French mime artist who created the character Bip |
| 37% | VALENTI | 7 | Jack who created the film rating system |
| 36% | SEARLE | 6 | English illustrator who created the "St. Trinian's" cartoon series |
| 35% | JIMHENSON | 9 | The man who created the Muppets characters |
| 35% | POE | 3 | Edgar Allan ___, author who created the character of C. Auguste Dupin, a precursor to Sherlock Holmes |
| 35% | LOUISAMAYALCOTT | 15 | Author who created the characters named by the starts of 17-, 24-, 49- and 61-Across |
| 35% | BEATRIXPOTTER | 13 | Author/illustrator who created the title character of 18-Across: 2 wds. |
| 34% | AVA | 3 | Director DuVernay who created the OWN series "Queen Sugar" |
| 34% | AVA | 3 | Director DuVernay who created the TV series "Queen Sugar" |
| 34% | ANTONCHEKHOV | 12 | Russian writer who created the characters played by 15-Across, 40-Across, and 45-Across in "The Seagull" |
| 34% | ELSA | 4 | Animated character who created the snowman Olaf |
| 34% | STANSMITH | 9 | The cartoon character who is American Dad |
| 34% | NELL | 4 | ___ Brinkley, female comic artist and illustrator who created the comic character "The Brinkley Girl" |