| 100% | LYNDONJOHNSON | 13 | Texan who resigned his Senate seat to become John F. Kennedy's vice president: 2 wds. |
| 68% | WALTERMONDALE | 13 | Minnesotan who resigned his Senate seat to become Jimmy Carter's vice president: 2 wds. |
| 45% | KAMALA | 6 | With 44-Across, Californian who resigned her Senate seat to become Joe Biden's vice president |
| 39% | LYNDONBJOHNSON | 14 | US vice president who became president upon the death of John F. Kennedy in 1963: 3 wds. |
| 32% | CALVINCOOLIDGE | 14 | US vice president who became president upon the death of Warren Harding in 1923: 2 wds. |
| 31% | WARRENGHARDING | 14 | U.S. president who, in 1922, became the first president to have his voice transmitted on the radio (3 wds.) |
| 30% | HARRYS | 6 | With 40-Across, US vice president who became president upon the death of Franklin D. Roosevelt in 1945: 2 wds. |
| 29% | MONDALE | 7 | Vice president who became ambassador to Japan |
| 28% | ROBERTFROST | 11 | Poet who read "The Gift Outright" at John F. Kennedy's inauguration (2 wds.) |
| 28% | SWEETCAROLINE | 13 | Neil Diamond song inspired by John F. Kennedy's daughter (2 wds.) |
| 28% | JAMESMARSDEN | 12 | "X-Men" actor who plays John F. Kennedy in "The Butler": 2 wds. |
| 28% | WALTERMONDALE | 13 | Vice president under Jimmy Carter from 1977 to 1981: 2 wds. |
| 28% | SPIROAGNEW | 10 | Vice president under Richard Nixon from 1969 to 1973: 2 wds. |
| 28% | PERON | 5 | 1940s vice president who went on to become president |
| 28% | JOEBIDEN | 8 | Barack Obama's vice president: 2 wds. |
| 28% | ALGORE | 6 | Bill Clinton's vice president: 2 wds. |
| 27% | DICKCHENEY | 10 | Vice president under George W. Bush from 2001 to 2009: 2 wds. |
| 27% | LYNDONJOHNSON | 13 | Texas senator who went on to become the 36th US president: 2 wds. |
| 26% | BURR | 4 | First U.S. vice president not to become president |
| 25% | BARACKOBAMA | 11 | Former U.S. President honored with the 2017 John F. Kennedy Profile in Courage Award (2 wds.) |
| 25% | ALGORE | 6 | Former vice president who wrote "An Inconvenient Truth" (2 wds.) |
| 25% | JOSEPHRBIDEN | 12 | Former vice president who is the oldest person to be inaugurated as president of the United States (3 wds.) |
| 24% | UNCLE | 5 | John F. Kennedy, to Maria Shriver |
| 24% | AGNEW | 5 | Vice president who resigned |
| 24% | CLIFFROBERTSON | 14 | "Charly" actor who played president-to-be John Kennedy in "PT 109" (1963): 2 wds. |
| 24% | DALLAS | 6 | Vice president after whom a U.S. city is thought to have been named |
| 24% | SPIRO | 5 | With 60-Across, one of two U.S. vice presidents to resign from office |
| 24% | ALEXTREBEK | 10 | "Jeopardy!" host who dropped his first name of George to go by his middle name's nickname: 2 wds. |
| 24% | AGNEW | 5 | Vice president who resigned in 1973 |