| 100% | BIGAPPLE | 8 | The ___ (fruity nickname for New York City): 2 wds. |
| 67% | BIGAPPLE | 8 | New York City's nickname, with "The" (2 wds.) |
| 64% | VAMPIREWEEKEND | 14 | New York City rock band whose last two albums each won the Grammy Award for Best Alternative Music Album (2 wds.) |
| 63% | THEMET | 6 | Major art museum in New York City, for short: 2 wds. |
| 63% | APPLE | 5 | The Big ___, nickname for New York City, New York that was popularized in the '20s |
| 63% | BIGAPPLE | 8 | Nickname for New York City |
| 63% | THEBIGAPPLE | 11 | Nickname for New York City |
| 63% | THEBIGAPPLE | 11 | Nickname for New York City that was first popularized by John Fitz Gerald and was a part of an ad campaign: 3 wds. |
| 61% | BIG | 3 | ___ Apple, nickname for New York City |
| 60% | GOTHAM | 6 | Nickname for New York City popularised by writer Washington Irving |
| 60% | GOTHAM | 6 | Nickname for New York City popularized by writer Washington Irving |
| 60% | STATUEOF | 8 | The ___ Liberty (famous New York City landmark): 2 wds. |
| 60% | BIG | 3 | With 4-Across, nickname for New York City |
| 60% | BIGAPPLE | 8 | Fruity nickname of New York City |
| 60% | THERAMONES | 10 | Punk band from New York City whose four unrelated members used the same last name: 2 wds. |
| 59% | CYNTHIANIXON | 12 | "Sex and the City" actress who unsuccessfully ran for New York governor in 2018: 2 wds. |
| 57% | THEBRONX | 8 | Northernmost borough of New York City: 2 wds. |
| 57% | DWIGHTGOODEN | 12 | Pitcher for the 1986 World Series champion New York Mets who was nicknamed "Dr. K": 2 wds. |
| 57% | REGGIEJACKSON | 13 | Former New York Yankees player who was nicknamed "Mr. October" for his postseason clutch hitting: 2 wds. |
| 57% | EDKOCH | 6 | Former New York City mayor known for asking "How'm I doin'?" (2 wds.) |
| 56% | MATTHARVEY | 10 | New York Mets pitcher who is nicknamed "The Dark Knight": 2 wds. |
| 56% | RUDYGIULIANI | 12 | New York City mayor, 1994-2001: 2 wds. |
| 56% | MIKEBLOOMBERG | 13 | New York City mayor, 2002-2013: 2 wds. |
| 56% | BIGEASY | 7 | With "the," nickname for New Orleans: 2 wds. |
| 55% | THEADDRESS | 10 | Novel by 39-Across set in New York City's apartment building The Dakota (2 wds.) |
| 54% | THEJEFFERSONS | 13 | Sitcom set in New York city that was a spin-off of "All in the Family" (2 wds.) |
| 54% | OLDGLORY | 8 | Nickname for the American flag: 2 wds. |
| 54% | LINCOLNTUNNEL | 13 | Passage from New York to New Jersey named for the 16th president (2 wds.) |
| 54% | JOETORRE | 8 | Player-manager for the New York Mets, 1977: 2 wds. |
| 53% | IGORSHESTERKIN | 14 | New York Rangers goalie honored with the Vezina Trophy for the NHL's 2021-22 season (2 wds.) |