| 100% | RATS | 4 | The —, 1974 debut novel by James Herbert |
| 63% | SPEAR | 5 | The —, 1978 novel by James Herbert |
| 60% | SECRETOF | 8 | & 22D The —, 2006 novel by James Herbert |
| 58% | ASH | 3 | 2012 novel by James Herbert |
| 54% | CARRIE | 6 | 1974 debut novel by Stephen King with a film adaptation starring Sissy Spacek |
| 51% | WYANDOTTE | 9 | 1843 novel by James Fenimore Cooper subtitled The Hutted Knoll |
| 49% | BEACH | 5 | The —, 1996 debut novel by Alex Garland |
| 49% | DESCENDANT | 10 | The —, 1897 debut novel by Ellen Glasgow |
| 49% | KITERUNNER | 10 | The —, 2003 debut novel by Khaled Hosseini |
| 49% | MONKEYKING | 10 | The —, 1978 debut novel by Timothy Mo |
| 49% | AURORADAWN | 10 | Debut novel by 43-Across subtitled "Or, the True History of Andrew Reale" (2 wds.) |
| 49% | SERENADE | 8 | 1937 novel by James M Cain narrated by the character John Howard Sharp |
| 48% | KILLINGFLOOR | 12 | Debut novel by 25-Across that was the basis for the first season of "Reacher" (2 wds.) |
| 48% | OCEAN | 5 | The —, 1941 novel by James Hanley |
| 48% | BLACKDAHLIA | 11 | The —, 1987 novel by James Ellroy |
| 47% | RODERICK | 8 | & 6D 1875 novel by Henry James featuring the character Rowland Mallet |
| 47% | REDROVER | 8 | The —, 1827 novel by James Fenimore Cooper |
| 47% | BUTTERFLY | 9 | The —, 1947 novel by James M Cain |
| 47% | AMERICANWOMAN | 13 | Novel by 52-Across based on the 1974 kidnapping of Patty Hearst (2 wds.) |
| 47% | DEADSIMPLE | 10 | 2005 novel by Peter James; first book in the Roy Grace series |
| 46% | MONSIEUR | 8 | 1974 novel by Lawrence Durrell subtitled The Prince of Darkness |
| 45% | GAIN | 4 | Novel by Richard Powers that won the James Fenimore Cooper Prize for Best Historical Fiction in 1999 |
| 45% | BOSTONIANS | 10 | The —, 1886 novel by Henry James |
| 45% | TRAGICMUSE | 10 | The —, 1890 novel by Henry James |
| 45% | ASPERNPAPERS | 12 | The —, 1888 novel by Henry James |
| 45% | AWKWARDAGE | 10 | The —, 1899 novel by Henry James |
| 44% | LIGHTHOUSE | 10 | The —, 2005 novel by P D James |
| 43% | FACTORY | 7 | The Wasp __, debut dystopian novel by Iain Banks |